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Chronic vagus nerve stimulation: a new and promising therapeutic approach for chronic heart failure.
AIMS In chronic heart failure (CHF), reduced vagal activity correlates with increased mortality and acute decompensation. Experimentally, chronic vagus nerve stimulation (VNS) improved leftExpand
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Vagus Nerve Stimulation for the Treatment of Heart Failure: The INOVATE-HF Trial.
BACKGROUND Heart failure (HF) is increasing in prevalence and is a major cause of morbidity and mortality despite advances in medical and device therapy. Autonomic imbalance, with excess sympatheticExpand
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Investigation of a novel algorithm for synchronized left-ventricular pacing and ambulatory optimization of cardiac resynchronization therapy: results of the adaptive CRT trial.
BACKGROUND In patients with sinus rhythm and normal atrioventricular conduction, pacing only the left ventricle with appropriate atrioventricular delays can result in superior left ventricular andExpand
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Clinical outcomes with synchronized left ventricular pacing: analysis of the adaptive CRT trial.
BACKGROUND Acute studies have suggested that left ventricular pacing (LVP) may have benefits over biventricular pacing (BVP). The adaptive cardiac resynchronization therapy (aCRT) algorithm providesExpand
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Comparison of Two Strategies to Reduce Ventricular Pacing in Pacemaker Patients
Background: Managed Ventricular Pacing (MVP) and Search AV+ (SAV+) are two pacing algorithms designed to reduce ventricular pacing. MVP promotes conduction by operating in AAI/R mode with backupExpand
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MRI scanning in patients with new and existing CapSureFix Novus 5076 pacemaker leads: randomized trial results.
BACKGROUND Magnetic resonance imaging (MRI) can be safely performed in patients with magnetic resonance (MR)-conditional pacemaker systems but remains relatively contraindicated withExpand
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Percent ventricular pacing with managed ventricular pacing mode in standard pacemaker population.
AIMS Unnecessary right ventricular pacing has deleterious effects and becomes more significant when cumulative percent ventricular pacing (Cum%VP) exceeds 40% of time. The Managed Ventricular PacingExpand
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Bidirectional Cardio-Respiratory Interactions in Heart Failure
We investigated cardio-respiratory coupling in patients with heart failure by quantification of bidirectional interactions between cardiac (RR intervals) and respiratory signals with complementaryExpand
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A Multicenter Study of Shock Pathways for Subcutaneous Implantable Defibrillators
A purely subcutaneous implantable cardioverter defibrillator (ICD) requires higher energy but may be an effective alternative to transvenous ICDs to deliver lifesaving therapies.
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[Echocardiographic evaluation of cardiac resynchronization therapy].
INTRODUCTION Cardiac resynchronization therapy (CRT) is relatively new tool in treatment of chronic heart failure (HF), especially in dilated cardiomyopathy (DCM) with the left bundle branch blockExpand
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