• Publications
  • Influence
Analysis of radioligand binding experiments. A collection of computer programs for the IBM PC.
  • G. McPherson
  • Computer Science, Medicine
  • Journal of pharmacological methods
  • 1 November 1985
This paper describes a collection of four programs (KINETIC, EBDA, LIGAND, and LOWRY) that can be used to analyze most forms of radioligand binding experiments. Expand
  • 1,174
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A practical computer-based approach to the analysis of radioligand binding experiments.
  • G. McPherson
  • Computer Science, Medicine
  • Computer programs in biomedicine
  • 1 August 1983
EBDA is a computer program designed to process raw data (dpm) obtained from radioligand binding experiments into a form suitable for use by a non-linear curve fitting program. Expand
  • 789
  • 13
Heart Rate Spectral Analysis, Cardiac Norepinephrine Spillover, and Muscle Sympathetic Nerve Activity During Human Sympathetic Nervous Activation and Failure
Although heart rate variability (HRV) at 0.1 Hz has been proposed as a noninvasive clinical measure of cardiac sympathetic nerve firing, this premise has not been sufficiently validated by comparisonExpand
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  • PDF
Carcinoma of the gallbladder and extrahepatic bile ducts.
  • 121
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Evidence that nitric oxide does not mediate the hyperpolarization and relaxation to acetylcholine in the rat small mesenteric artery
1 Acetylcholine caused a concentration‐dependent smooth muscle hyperpolarization and relaxation in rat small mesenteric arteries (diameter at 100 mmHg 250–450 mm) stimulated with noradrenaline (3Expand
  • 360
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Pre‐operative percutaneous transhepatic biliary drainage: The results of a controlled trial
The operative mortality for biliary tract obstruction due to malignancy is high. In 1981 a controlled clinical trial of pre‐operative percutaneous drainage was started at the Royal PostgraduateExpand
  • 360
  • 3
Percutaneous transhepatic drainage in obstructive jaundice: Advantages and problems
This study is a critical prospective assessment of 37 patients with obstructive jaundice, treated by percutaneous transhepatic biliary drainage. The median duration of drainage was 18 days (rangeExpand
  • 103
  • 3
Sympathetic control of cerebral arteries: specialization in receptor type, reserve, affinity, and distribution
The sympathetic neuroeffector system in the mammalian cerebral circulation has a number of distinctive features that reflect its specialized role in this vascular bed: 1) there is limitedExpand
  • 82
  • 3
Characterization of KATP channels in intact mammalian skeletal muscle fibres
1 The aim of this study was to characterize the KATP channel of intact rat skeletal muscle (rat flexor digitorum brevis muscle). Changes in membrane currents were recorded with two‐electrodeExpand
  • 33
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  • G. McPherson
  • Chemistry, Medicine
  • Clinical and experimental pharmacology…
  • 1 December 1992
1. Using a small vessel myograph, experiments were performed on rat small mesenteric arteries (and in some cases dog small coronary arteries) to assess the dependence of vasoconstrictor potencyExpand
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