• Publications
  • Influence
Staging of chronic nonsuppurative destructive cholangitis (syndrome of primary biliary cirrhosis)
TLDR
Staging of liver biopsy specimens from patients with chronic non-suppurative destructive cholangitis (CNDC) has become an important part of clinical studies that are currently done in many centers, and methods based on uniform criteria that are applicable to all specimens and are easily reproducible are suggested. Expand
Distinct MHC class I and II alleles are associated with hepatitis C viral clearance, originating from a single source
TLDR
Certain class I alleles are associated with outcome in this homogenous cohort of females inoculated with HCV genotype 1b and either HLA‐A*03, ‐DRB1*0101, or ‐*0401 are carried by the overwhelming majority of those subjects who successfully clear HCV. Expand
Guided versus blind liver biopsy for chronic hepatitis C: clinical benefits and costs.
TLDR
Even in the absence of major complications, ultrasound-guided liver biopsy with an automated needle in HCV patients is safer, more comfortable and only marginally more expensive than blind Trucut biopsy. Expand
The development of hepatic granulomas following interferon-alpha2b therapy for chronic hepatitis C infection.
TLDR
It is suggested that IFN alpha may have a biological role in the pathogenesis of granulomatous liver disease in these patients, in whom hepatic granulomas were absent on initial liver biopsies, but in whomgranulomas developed following IFNalpha therapy. Expand
Passive immunisation of hamsters against Clostridium difficile infection using antibodies to surface layer proteins.
TLDR
It is indicated that anti-SLP antibodies can modulate the course of C. difficile infection and may therefore merit closer investigation for use as constituents of multi-component vaccines against C.difficile associated diarrhoea. Expand
The MHC is a major determinant of viral status, but not fibrotic stage, in individuals infected with hepatitis C.
TLDR
It is shown that in a homogenous cohort of women infected with the same hepatitis C virus, several HLA antigens are associated with either viral clearance or persistence, which suggests a strong role for host immunogenetic factors in determining outcome in hepatitis C infection. Expand
Passive immunisation of hamsters against Clostridium difficile infection using antibodies to surface layer proteins
TLDR
It is indicated that anti-SLP antibodies can modulate the course of C. difficile infection and may therefore merit closer investigation for use as constituents of multi-component vaccines against C.difficile associated diarrhoea. Expand
Immunological indicators of coeliac disease activity are not altered by long‐term oats challenge
TLDR
It is suggested that the antigenic stimulus caused by wheat exposure differs fundamentally from that caused by oats, and the lack of oats immunogenicity and toxicity to coeliac patients is reaffirmed. Expand
Copper stains and the syndrome of primary biliary cirrhosis. Evaluation of staining methods and their usefulness for diagnosis and trials of penicillamine treatment.
TLDR
Use of Shikata's stain was found to be a sensitive method for the demonstration of copper-protein complexes, but use of the rhodamine stain may be more reliable because it seemed adequate to evaluate penicillamine treatment trials. Expand
...
1
2
3
...