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Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort
Summary Background Medulloblastoma is associated with rare hereditary cancer predisposition syndromes; however, consensus medulloblastoma predisposition genes have not been defined and screening… Expand
Prevalence of bronchial hyperresponsiveness and asthma in a rural adult population.
The prevalence of bronchial hyperresponsiveness in adult populations is not known. To document its prevalence and distribution and to determine the factors associated with it, a random sample of the… Expand
Intensive induction chemotherapy followed by high dose chemotherapy with autologous hematopoietic progenitor cell rescue in young children newly diagnosed with central nervous system atypical…
- S. Gardner, S. Asgharzadeh, A. Green, B. Horn, G. McCowage, J. Finlay
- Pediatric blood & cancer
- 1 August 2008
Central nervous system (CNS) atypical teratoid rhabdoid tumors (AT/RT) are rare tumors of childhood with a dismal prognosis. Historically, surgery and standard dose chemotherapy have resulted in a… Expand
Monitoring of neoadjuvant therapy response of soft-tissue and musculoskeletal sarcoma using fluorine-18-FDG PET.
- D. N. Jones, G. McCowage, +9 authors R. Coleman
- Journal of nuclear medicine : official…
- 1 September 1996
UNLABELLED The purpose of this study was to investigate the potential role of FDG-PET in the monitoring of neoadjuvant therapy of soft-tissue and musculoskeletal sarcomas. METHODS Nine patients… Expand
Limb preservation surgery with extracorporeal irradiation in the management of malignant bone tumor: the oncological outcomes of 101 patients.
- A. Hong, S. Millington, +5 authors P. Stalley
- Annals of oncology : official journal of the…
- 1 October 2013
BACKGROUND En bloc resection, extracorporeal irradiation (ECI) and reimplantation have been used selectively at our centers as part of limb preservation surgery of malignant bone tumors since 1996.… Expand
Buccal swabs and treated cards: methodological considerations for molecular epidemiologic studies examining pediatric populations.
- Sara M Beckett, Stephen J Laughton, +5 authors L. Ashton
- American journal of epidemiology
- 15 May 2008
Self-collection of buccal cells provides a noninvasive method for obtaining biologic samples for genetic analyses in pediatric studies. Nevertheless, low yields, microbial contamination, and… Expand
Rasburicase (recombinant urate oxidase) for the management of hyperuricemia in patients with cancer
Hyperuricemia and tumor lysis syndrome (TLS) are serious complications that can occur during chemotherapy for hematologic malignancies, even if standard management procedures, including… Expand
Phase II, Open-Label, Randomized, Multicenter Trial (HERBY) of Bevacizumab in Pediatric Patients With Newly Diagnosed High-Grade Glioma.
- J. Grill, M. Massimino, +17 authors G. Vassal
- Journal of clinical oncology : official journal…
- 7 February 2018
Purpose Bevacizumab (BEV) is approved in more than 60 countries for use in adults with recurrent glioblastoma. We evaluated the addition of BEV to radiotherapy plus temozolomide (RT+TMZ) in pediatric… Expand
Systemic therapy in neurofibromatosis type 2.
- S. Lim, Simone L. Ardern-Holmes, G. McCowage, P. de Souza
- Cancer treatment reviews
- 1 August 2014
The systemic treatment of patients with neurofibromatosis type 2 associated tumours is challenging, as these patients often have prolonged survival but with the inevitable propensity for their… Expand
It is ALL in the Heart: A Patient with Acute Lymphoblastic Leukemia and Cardiac Infiltration at Time of Diagnosis
We report an unusual case of acute lymphoblastic leukemia (ALL) in a 15-year-old boy where a mass lesion, presumed to be a cardiac metastasis, was noted in the right ventricular wall and cavity at… Expand