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A 3-year naturalistic study of 53 preschool children with pervasive developmental disorders treated with risperidone.
TLDR
It is suggested that low-dose risperidone may positively affect the clinical outcome in young children with PDD not only in the short-term, but also in the long-term period. Expand
A naturalistic study of referred children and adolescents with obsessive-compulsive disorder.
TLDR
Long-term naturalistic prospective studies in pediatric patients with OCD might represent an important source of information for everyday care regarding the effectiveness of a treatment over extended periods of time under routine clinical conditions. Expand
Open trial of risperidone in 24 young children with pervasive developmental disorders.
TLDR
Low-dose risperidone may positively affect symptoms in young autistic children, improving disruptive/hyperactive behavior and affective dysregulation and further controlled studies in this age group are warranted. Expand
Generalized anxiety disorder in referred children and adolescents.
TLDR
Referred children and adolescents with generalized anxiety disorder are heavily symptomatic and have frequent comorbidity, which may help early diagnosis and prevention of superimposed mental disorders. Expand
A Naturalistic Exploratory Study of the Impact of Demographic, Phenotypic and Comorbid Features in Pediatric Obsessive-Compulsive Disorder
TLDR
These characteristics of OCD in the framework of the 4 OCD phenotypes (contamination/cleaning, order/symmetry, obsessions/checking and hoarding) proposed by Leckman et al may have marked clinical and prognostic implications. Expand
The Hippocampus, Neurotrophic Factors and Depression
TLDR
The above findings suggest new possible targets for the pharmacotherapy of depression such as neurotrophic factors, their receptors and related intracellular signalling cascades; agents counteracting the effects of stress on hippocampal neurogenesis; and agents facilitating the activation of gene expression and increasing the transcription of neurotrophins in the brain. Expand
Obsessive-compulsive bipolar comorbidity: focus on children and adolescents.
TLDR
Co-morbidity between OCD and BP is a significant clinical problem affecting a large number of patients and has relevant clinical implications as far as other concomitant disorders, symptomatological features, course, complications, and treatment management and outcome are concerned. Expand
Attention-deficit hyperactivity disorder -- bipolar comorbidity in children and adolescents.
TLDR
Attention-deficit hyperactivity disorder comorbidity is frequent in juvenile bipolar disorder and can influence age of onset, phenomenology, comor bidity, and course of BD. Expand
Comorbidity of obsessive-compulsive disorder and attention-deficit/hyperactivity disorder in referred children and adolescents.
TLDR
A screening for ADHD should be performed in patients with OCD, as these patients and their parents are frequently not aware that the impairment may be partly due to a comorbid ADHD. Expand
Bipolar disorder in adults with Asperger׳s Syndrome: a systematic review.
TLDR
BD in AS patients is frequent, usually it onsets during adolescence and is often characterized by atypical presentation, making its correct identification particularly difficult, and a correct diagnosis of BD in AS individuals has relevant implications on the choice of adequate psychopharmacological, psycho-social and rehabilitative treatments. Expand
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