G. Malhi

Publications789
h-index79
Citations22,688
Highly Influential Citations900
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Pathways underlying neuroprogression in bipolar disorder: Focus on inflammation, oxidative stress and neurotrophic factors
TLDR
Emerging data shows that these biomarkers may differ between early and late stages of BD in parallel with stage-related structural and neurocognitive alterations, which facilitates identification of rational therapeutic targets, and the development of novel treatment classes. Expand
Implications of childhood trauma for depressed women: an analysis of pathways from childhood sexual abuse to deliberate self-harm and revictimization.
TLDR
Depressed women with a childhood sexual abuse history constitute a subgroup of patients who may require tailored interventions to combat both depression recurrence and harmful and self-defeating coping strategies, and are an important risk factor to identify in women with depression. Expand
The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders.
TLDR
A consensus was reached on 12 statements on the use of antidepressants in bipolar disorder, and antidepressants should be prescribed only as an adjunct to mood-stabilizing medications. Expand
Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders
TLDR
The Mood Disorder CPG is the first Clinical Practice Guideline to address both depressive and bipolar disorders and provides up-to-date recommendations and guidance within an evidence-based framework, supplemented by expert clinical consensus. Expand
An emotional Stroop functional MRI study of euthymic bipolar disorder.
TLDR
Euthymic bipolar patients are perhaps constrained in their ability to engage affective processing, suggesting that 'all is not well in euthymia', although the effects of medication cannot be overlooked. Expand
A randomized controlled trial of cognitive therapy for bipolar disorder: focus on long-term change.
TLDR
The findings corroborate previous bipolar disorder research in demonstrating the value of CT, particularly immediately post-treatment, and indicate some continuation of benefits in the succeeding 12 months, and suggest that psychological booster sessions may be crucial for maintaining the beneficial effects of cognitive therapy. Expand
Neuropsychological deficits and functional impairment in bipolar depression, hypomania and euthymia.
TLDR
The possibility of persistent cognitive deficits in BD is an issue of profound clinical and research interest that warrants further investigation and future research needs to adopt more sophisticated neuropsychological probes that are able to better define state and trait deficits and determine their functional impact. Expand
The psychological and neurophysiological concomitants of mindfulness forms of meditation
TLDR
Preliminary findings from treatment outcome studies provide support for the application of mindfulness-based interventions in the treatment of affective, anxiety and personality disorders, however, direct evidence for the effectiveness of mindfulness meditation per se in the Treatment of psychiatric disorders is needed. Expand
Functional outcome in bipolar disorder: the role of clinical and cognitive factors.
TLDR
Low-functioning patients were cognitively more impaired than highly functioning patients on verbal recall and executive functions and the variable that best predicted psychosocial functioning in bipolar patients was verbal memory. Expand
The promise of N-acetylcysteine in neuropsychiatry.
TLDR
The efficacy pattern of NAC interestingly shows little respect for the current diagnostic systems, and its benign tolerability profile, its action on multiple operative pathways, and the emergence of positive trial data make it one of the most promising drug candidates in neuropsychiatric disorders. Expand
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