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Hypotensive and vasorelaxant effects of the procyanidin fraction from Guazuma ulmifolia bark in normotensive and hypertensive rats.
Guazuma ulmifolia bark possesses long-lasting antihypertensive and vasorelaxing properties linked to the endothelium related factors, where nitric oxide is involved.
Pharmacology of Casimiroa edulis; III. Relaxant and contractile effects in rat aortic rings.
The relaxant and contractile effects of an aqueous extract of the seeds of the hypotensive plant Casimiroa edulis were investigated in rat aortic rings and it was concluded that the relaxant effect is not exerted through release of an endothelial relaxing factor nor through blockade of calcium channels or of specific smooth muscle receptors, and does not involve histaminergic mechanisms.
Pharmacology of Casimiroa edulis; Part I. Blood pressure and heart rate effects in the anesthetized rat.
Experiments revealed that extract-induced hypotension was not mediated by histamine H2, muscarinic, or beta-adrenergic receptors, but involved an H1 mechanism and it was suggested that imidazole derivatives could be responsible for the depressor effect observed.
Pharmacology of Casimiroa edulis IV. Hypotensive effects of compounds isolated from methanolic extracts in rats and guinea pigs.
It was concluded that hypotension produced by C. edulis is due to several active components, including histamine derivatives acting on H1-receptors and casimiroedine, which is partially offset by synephrine acetonide through adrenergic mechanisms.
The unambiguous detection of kaurenic derivatives in aqueous infusions of Montanoa tomentosa by GC-MS and 2D-NMR spectroscopy: an answer to contradictory reports.
The qualitative analytical detection of kaurenic compounds kauradienoic and monoginoic in the infusion of Montanoa tomentosa Cerv.
Toluene and benzene inhalation influences on ventricular arrhythmias in the rat.
- G. Magos, M. Lorenzana-Jiménez, H. Vidrio
- Chemistry, MedicineNeurotoxicology and teratology
- 1 March 1990
Toluene did not share the capacity of benzene for increasing the arrhythmogenic action of epinephrine in the rat, but appeared to elicit the opposite effect, and gas chromatographic measurement of toluene levels in the heart during and after inhalation revealed essentially constant concentrations at the time of arrhythmia evaluation.
Isolation and characterization of cytotoxic and antibacterial tetrasaccharide glycosides from Ipomoea stans.
- W. Reynolds, M. Yu, +4 authors M. Villareal
- Biology, MedicineJournal of natural products
- 1 November 1995
Three new tetrasaccharide glycosides, differing from one reported previously in the type of short-chain fatty acids ester-linked to the tetrasaccharide core, have been isolated and identified from an…
Pharmacology of Casimiroa edulis; II. Cardiovascular effects in the anesthesized dog.
It was concluded that the cardiovascular pattern of Casimiroa edulis in the dog is that of a peripheral arterial vasodilator and that it increases cardiac output by reducing left ventricular afterload.
Electrocardiographic effects of toluene in the anesthetized rat.
- H. Vidrio, G. Magos, M. Lorenzana-Jiménez
- Chemistry, MedicineArchives internationales de pharmacodynamie et de…
The results suggest that toluene administered by inhalation up to near lethal doses is devoid of untoward ECG effect in the chloralose-anesthetized rat, its only action being a decrease in intraventricular and particularly AV conduction.
Repeated administration of adenosine increases its cardiovascular effects in rats.
Hypotensive and negative chronotropic responses to adenosine in anesthetized rats increased after previous administration of the nucleoside and self-potentiation could be due to extracellular accumulation ofAdenosine and persistent stimulation of receptors caused by saturation or inhibition of cellular uptake ofadenosine.