G. Mackaness

Publications130
h-index36
Citations7,404
Highly Influential Citations121
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  • Publications
  • Influence
CELLULAR RESISTANCE TO INFECTION
  • G. Mackaness
  • Biology, Medicine
  • The Journal of experimental medicine
  • 1 September 1962
The mouse was found to be natively susceptible to Listeria monocytogenes. Its susceptibility was attributed to the capacity of the organism to survive and multiplying in host macrophages. During the… Expand
  • 1,214
  • 23
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THE INFLUENCE OF IMMUNOLOGICALLY COMMITTED LYMPHOID CELLS ON MACROPHAGE ACTIVITY IN VIVO
  • G. Mackaness
  • Biology, Medicine
  • The Journal of experimental medicine
  • 1 May 1969
It has been shown that the immune response of mice to infection with L. monocytogenes gives rise to a population of immunologically committed lymphoid cells which have the capacity to confer… Expand
  • 779
  • 15
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THE IMMUNOLOGICAL BASIS OF ACQUIRED CELLULAR RESISTANCE
  • G. Mackaness
  • Biology, Medicine
  • The Journal of experimental medicine
  • 1 July 1964
The resistance developed by mice during infection with Listeria monocytogenes, Brucella abortus, or Mycobacterium tuberculosis is not specifically directed against the infecting organism. The… Expand
  • 668
  • 13
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INFLUENCE OF DOSE AND ROUTE OF ANTIGEN INJECTION ON THE IMMUNOLOGICAL INDUCTION OF T CELLS
Delayed-type hypersensitivity (DTH) develops in the absence of an adjuvant when mice are injected intravenously or subcutaneously with an appropriate dose of sheep red blood cells (SRBC). The optimal… Expand
  • 313
  • 6
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THE HOST RESPONSE TO CALMETTE-GUÉRIN BACILLUS INFECTION IN MICE
Heterologous organisms (L. monocytogenes and S. typhimurium) were used to study the rate of development, magnitude, and persistence of the antimicrobial resistance engendered in mice by vaccination… Expand
  • 233
  • 6
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POTENTIATION OF T-CELL-MEDIATED IMMUNITY BY SELECTIVE SUPPRESSION OF ANTIBODY FORMATION WITH CYCLOPHOSPHAMIDE
Delayed-type hypersensitivity (DTH) appears in mice immunized with less than an optimal immunogenic dose of sheep red blood cells (SRBC), but is blocked progressively as antibody production increases… Expand
  • 270
  • 5
  • PDF
Resistance to intracellular infection.
  • G. Mackaness
  • Biology, Medicine
  • The Journal of infectious diseases
  • 1 April 1971
charged by cells without help from humoral factors, cells do serve, as functional entities, in the mediation and expression of an important mechanism of acquired resistance. They assume particular… Expand
  • 230
  • 5
MECHANISMS OF ACQUIRED RESISTANCE IN MOUSE TYPHOID
Experiments in vitro comparing normal mouse peritoneal macrophages with cells from Salmonella typhimurium-infected mice have shown that the "immune" macrophages have conspicuously enhanced… Expand
  • 220
  • 5
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The action of drugs on intracellular tubercle bacilli.
  • G. Mackaness
  • Biology, Medicine
  • The Journal of pathology and bacteriology
  • 1 July 1952
  • 136
  • 4
HOST-PARASITE RELATIONS IN MOUSE TYPHOID
The development of acquired resistance to Salmonella typhimurium has been studied in mice infected intravenously with small numbers of streptomycin-sensitive or streptomycin-resistant organisms. By… Expand
  • 176
  • 4
  • PDF