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Lower hippocampal volume in patients suffering from depression: a meta-analysis.
TLDR
A meta-analysis of studies that used magnetic resonance imaging to assess the volume of the hippocampus and related structures in patients with major depressive disorder found inclusion of the amygdala with the hippocampus appears to have decreased the likelihood of detecting volumetric differences in either structure.
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar
The Canadian Network for Mood and Anxiety Treatments published guidelines for the management of bipolar disorder in 2005, with updates in 2007 and 2009. This third update, in conjunction with the
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder
TLDR
These 2018 CANMAT and ISBD Bipolar Treatment Guidelines represent the significant advances in the field since the last full edition was published in 2005, including updates to diagnosis and management as well as new research into pharmacological and psychological treatments.
Bacterial infection causes stress-induced memory dysfunction in mice
TLDR
Memory dysfunction occurs in infected mice exposed to acute stress, while in the germ-free setting memory is altered at baseline, suggesting the intestinal microbiota influences the ability to form memory.
A meta-analysis examining clinical predictors of hippocampal volume in patients with major depressive disorder.
TLDR
The results suggest that hippocampal volume reductions generally occur after disease onset in patients with MDD, and have implications for the timing of clinical interventions aimed at reducing the impact of MDD on neuronal structure and function.
Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder
TLDR
Despite the limited evidence base, extant data and clinical experience suggest that each of these special populations can benefit from the systematic application of treatment guidelines for treatment of MDD.
Course of illness, hippocampal function, and hippocampal volume in major depression
TLDR
Comparing hippocampal function, as assessed by performance on hippocampal-dependent recollection memory tests, and hippocampal volumes, as measured in a 1.5-T magnetic resonance imager, in depressed subjects experiencing a postpubertal onset of depression revealed a significant logarithmic association between illness duration and hippocampusal volume.
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar
The Canadian Network for Mood and Anxiety Treatments (CANMAT) published guidelines for the management of bipolar disorder in 2005, with a 2007 update. This second update, in conjunction with the
The hippocampus in major depression: evidence for the convergence of the bench and bedside in psychiatric research?
TLDR
The clinical and biological correlates of small hippocampal volumes based on literature searches of PubMed and EMBASE are reviewed and the ways in which these data force a re-conceptualization of MDD are discussed.
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