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Acetaminophen prodrugs. I. Synthesis, physicochemical properties, and analgesic activity.
- L. Dittert, H. C. Caldwell, H. J. Adams, G. M. Irwin, J. V. Swintosky
- Chemistry, BiologyJournal of pharmaceutical sciences
- 1 May 1968
TLDR
Enhancement of gastrointestinal absorption of a quaternary ammonium compound by trichloroacetate.
- G. M. Irwin, H. Kostenbauder, L. Dittert, R. Staples, A. Misher, J. V. Swintosky
- Chemistry, BiologyJournal of pharmaceutical sciences
- 1 March 1969
TLDR
DRUG PARTITIONING. I. NONEMULSIFYING METHOD FOR MEASURING DISTRIBUTION COEFFICIENTS.
- D. R. Reese, G. M. Irwin, L. Dittert, C. W. Chong, J. V. Swintosky
- EngineeringJournal of pharmaceutical sciences
- 1 June 1964
TLDR
Colorimetric assay procedure for dissolution studies of meprobamate formulations.
- J. W. Poole, G. M. Irwin, S. Young
- ChemistryJournal of pharmaceutical sciences
- 1 December 1971
TLDR
4-acetamidophenyl 2,2,2-trichlorethyl carbonate synthesis, physical properties, and in vitro hydrolysis.
- J. V. Swintosky, H. C. Caldwell, C. W. Chong, G. M. Irwin, L. Dittert
- Chemistry, BiologyJournal of pharmaceutical sciences
- 1 May 1968
TLDR
Acetaminophen prodrugs. II. Effect of structure and enzyme source on enzymatic and nonenzymatic hydrolysis of carbonate esters.
- L. Dittert, G. M. Irwin, C. W. Chong, J. V. Swintosky
- BiologyJournal of pharmaceutical sciences
- 1 May 1968
TLDR
Carbonate ester prodrugs of salicylic acid. Synthesis, solubility characteristics, in vitro enzymatic hydrolysis rates, and blood levels of total salicylate following oral administration to dogs.
- L. Dittert, H. C. Caldwell, T. Ellison, G. M. Irwin, D. E. Rivard, J. V. Swintosky
- ChemistryJournal of pharmaceutical sciences
- 1 May 1968
TLDR
Encapsulation of clomacran phosphate [2-chloro-9[3-(dimethylamino) propyl]acridan phosphate] I. Effect of flowability of powder blends, lot-to-lot variability, and concentration of active ingredient…
- G. M. Irwin, G. J. Dodson, L. J. Ravin
- Chemistry, MedicineJournal of pharmaceutical sciences
- 1 April 1970
Abstract A correlation has been shown to exist between the flow properties of clomacran phosphate powder blends and capsule fill weight variation when an automatic capsule-filling machine is used.A…
Antacid Properties of Calcium, Magnesium, and Aluminum Salts of Water-Insoluble Aliphatic Acids
- S. Eriksen, G. M. Irwin, J. V. Swintosky
- Chemistry
- 1 June 1963
The antacid properties of several calcium, magnesium, and aluminum salts of aliphatic acids were studied. A number of the salts showed potential antacid properties in vitro . Of this group calcium…
Hydrolysis of 4-acetamidophenyl 2,2,2-trichloroethyl carbonate by esterolytic enzymes from various sources.
- L. Dittert, G. M. Irwin, E. Rattie, C. W. Chong, J. V. Swintosky
- Biology, ChemistryJournal of pharmaceutical sciences
- 1 May 1969
TLDR
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