The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism
Documenting the diet in ancient human populations through stable isotope analysis of hair.
- S. Macko, M. Engel, V. Andrusevich, G. Lubec, T. O’Connell, R. Hedges
- Environmental SciencePhilosophical transactions of the Royal Society…
- 29 January 1999
It is suggested that a commonly overlooked material, human hair, may represent an ideal material to be used in addressing human diets of ancient civilizations, and isotopically characterized modern individuals for whom the diet has been documented.
Barnes maze, a useful task to assess spatial reference memory in the mice
The effect of repeated ozone exposures on inflammatory markers in bronchoalveolar lavage fluid and mucosal biopsies.
- R. Jörres, O. Holz, H. Magnussen
- Medicine, BiologyAmerican Journal of Respiratory and Critical Care…
- 1 June 2000
It is demonstrated that airway inflammation persists after repeated ozone exposure, despite attenuation of some inflammatory markers in BALF and adaptation of lung function.
Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders
The Ice Man's diet as reflected by the stable nitrogen and carbon isotopic composition of his hair
- S. Macko, G. Lubec, M. Teschler-Nicola, V. Andrusevich, M. Engel
- Environmental Science, GeographyThe FASEB Journal
- 1 March 1999
It is reported that the stable carbon and nitrogen isotope values for the hair of the 5200 year‐old Ice Man indicates a primarily vegetarian diet, in agreement with his dental wear pattern.
On the Origin of Extracellular Glutamate Levels Monitored in the Basal Ganglia of the Rat by In Vivo Microdialysis
It is concluded that there is a pool of releasable Glu and Asp in the rat brain, and extracellular levels of amino acids monitored by in vivo microdialysis reflect the balance between neuronal release and reuptake into surrounding nerve terminals and glial elements.
Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling
The results, which provide a mechanistic link between myelin, a mediator of OPC differentiation inhibition associated with demyelinating pathologies and specific signalling pathways amenable to pharmacological manipulation, are of significant potential value for future strategies aimed at enhancing CNS remyelination.
Zinc deficiency induces enhanced depression-like behaviour and altered limbic activation reversed by antidepressant treatment in mice
Data support the link between low Zn levels and depression-like behaviour and suggest experimentally-induced Zn deficiency as a putative model of depression in mice.
Aberrant expression of cytoskeleton proteins in hippocampus from patients with mesial temporal lobe epilepsy
The findings may represent or lead to cytoskeletal impairment; aberrant antioxidant proteins, chaperons, MAP kinase kinase 1 and NAD-dependent deacetylase sirtuin-2 may have been involved in pathogenetic mechanisms and altered synaptosomal protein expression possibly reflects synaptic impairment in MTLE.