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Identification, isolation, and partial characterization of a fatty acid binding protein from rat jejunal microvillous membranes.
- W. Stremmel, G. Lotz, G. Strohmeyer, P. Berk
- Biology, Medicine
- The Journal of clinical investigation
- 1 March 1985
The mechanisms by which FFA are absorbed by the gut are unclear. To examine these processes, binding of [14C]oleate to isolated rat jejunal microvillous membranes (MVM) was studied in vitro. When… Expand
Claudin expression in pancreatic endocrine tumors as compared with ductal adenocarcinomas
Altered expression of recently described claudins (CLDNs) as members of tight junction (TJ) transmembrane proteins was noted in several malignancies. We aimed to analyze protein and messenger RNA… Expand
Clinical significance of genetic alterations and expression of epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinomas.
The significance of epidermal growth factor receptor (EGFR) signaling is well studied in a number of different tumors, but limited data is available with regard to head and neck squamous cell… Expand
BGP-15 inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury.
- G. Nagy, A. Szarka, +9 authors J. Mandl
- Chemistry, Medicine
- Toxicology and applied pharmacology
- 15 February 2010
It has been recently shown that acute acetaminophen toxicity results in endoplasmic reticulum redox stress and an increase in cells with apoptotic phenotype in liver. Since activation of effector… Expand
Viral hepatitis: New data on hepatitis C infection
Viral hepatitis (VH) is almost as old as human beings, at least as old as known human history. However, the natural history and the epidemiology of the disease has undergone changes during the… Expand
Claudin 1 differentiates endometrioid and serous papillary endometrial adenocarcinoma.
OBJECTIVE The expression of claudins, the main tight junction proteins involved in cell adhesion and carcinogenesis, was studied in endometrioid (type I) and seropapillary (type II) endometrial… Expand
Tricellulin expression in normal and neoplastic human pancreas
Korompay A, Borka K, Lotz G, Somorácz Á, Törzsök P, Erdélyi‐Belle B, Kenessey I, Baranyai Z, Zsoldos F, Kupcsulik P, Bodoky G, Schaff Z & Kiss A
ADMA Impairs Nitric Oxide–Mediated Arteriolar Function Due to Increased Superoxide Production by Angiotensin II–NAD(P)H Oxidase Pathway
Asymmetrical dimethylarginine (ADMA) is thought to be an endogenous regulator of arteriolar tone by inhibiting NO synthase. However, our previous studies showed that, in isolated arterioles, ADMA… Expand
Different Expression of Occludin and ZO-1 in Primary and Metastatic Liver Tumors
Tight junction (TJ) components were found to be correlated with carcinogenesis and tumor development. TJs are composed of three main integral membrane proteins; occludin, claudins and JAMs.… Expand
Distinct Claudin Expression Profiles of Hepatocellular Carcinoma and Metastatic Colorectal and Pancreatic Carcinomas
- Ágnes Holczbauer, Benedek Gyöngyösi, +4 authors A. Kiss
- Medicine, Biology
- The journal of histochemistry and cytochemistry…
- 1 April 2013
Tight junction proteins, including claudins, are often dysregulated during carcinogenesis and tumor progression. Moreover, the claudin expression pattern usually varies between different tumor… Expand