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Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study
Objective Low back pain (LBP) is a common musculoskeletal disorder, but it is still unclear which individuals develop it. The authors examined the contribution of genetic factors, lumbar discExpand
Sarcopenic obesity or obese sarcopenia: A cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the pathogenesis
Sarcopenia, an age-associated decline in skeletal muscle mass coupled with functional deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity and mortalityExpand
Decreased developmental stability as assessed by fluctuating asymmetry of morphometric traits in preterm infants.
Fluctuating asymmetry (FA) of 8 morphometric traits was studied in 113 preterm infants (26-36 wk of gestation), 103 term infants (37-41 wk), and their respective parents. With 3 different measures ofExpand
Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford study
Objective There is a great need for identification of biomarkers that could improve the prediction of early osteoarthritis (OA). We undertook this study to determine whether circulating levels ofExpand
Meta-Analysis of Genome-Wide Scans for Human Adult Stature Identifies Novel Loci and Associations with Measures of Skeletal Frame Size
Recent genome-wide (GW) scans have identified several independent loci affecting human stature, but their contribution through the different skeletal components of height is still poorly understood.Expand
Fluctuating asymmetry as a possible measure of developmental homeostasis in humans: a review.
We investigate three hypotheses related to fluctuating asymmetry (FA) of bilateral morphologic traits in humans: (1) the magnitude of FA in individual suffering from different levels of morbidity isExpand
Distribution of the 3' VNTR polymorphism in the human dopamine transporter gene in world populations.
A polymorphism with a variable number of tandem repeats (VNTR) found in the 3' untranslated region of the human dopamine transporter gene (DAT1) was scored in unrelated individuals drawn from 10Expand
Osteocyte control of bone remodeling: is sclerostin a key molecular coordinator of the balanced bone resorption–formation cycles?
Osteocytes, entrapped within a newly mineralized bone matrix, possess a unique cellular identity due to a specialized morphology and a molecular signature. These features endow them to serve as aExpand
Circulating levels of receptor activator of nuclear factor-kappaB ligand/osteoprotegerin/macrophage-colony stimulating factor in a presumably healthy human population.
OBJECTIVES To determine the ranges of variation of circulating receptor activator of nuclear factor-kappaB ligand (RANKL)/osteoprotegerin (OPG)/macrophage-colony stimulating factor(M-CSF) and toExpand
Study of genetic variance in the fluctuating asymmetry of anthropometrical traits.
We have studied the fluctuating asymmetry (FA) of 8 bilateral morphometric traits in two-parent families, comprising 216 families with one newborn baby, and 60 families with two children (age rangeExpand