G. Lim-Fong

Publications17
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Citations488
Highly Influential Citations45
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Treadmilling of a prokaryotic tubulin-like protein, TubZ, required for plasmid stability in Bacillus thuringiensis.
TLDR
The results suggest that TubZ is representative of a novel class of prokaryotic cytoskeletal proteins important for plasmid stability that diverged long ago from the ancient tubulin/FtsZ ancestor. Expand
Bryostatins: biological context and biotechnological prospects.
TLDR
Challenges in the development of bryostatins for biomedical and biotechnological application include the cultivation of the bacterial symbiont and heterologous expression of bRYostatin biosynthesis genes. Expand
Intracellular mobility of plasmid DNA is limited by the ParA family of partitioning systems
TLDR
Fluorescence recovery after photobleaching and time‐lapse microscopy is used to measure plasmid mobility in living E. coli cells and reveals an important function for Par systems inplasmid DNA segregation that is likely to be conserved in bacteria. Expand
Cryptic species in the cosmopolitan Bugula neritina complex (Bryozoa, Cheilostomata)
TLDR
Bayesian species delimitation analysis of a data set composed of two mitochondrial (COI and large ribosomal RNA subunit [16S]) and two nuclear genes demonstrated that Types S, D and N correspond to three biological species, which indicates that the Type N may also have been introduced widely. Expand
Evolutionary Relationships of “Candidatus Endobugula” Bacterial Symbionts and Their Bugula Bryozoan Hosts
TLDR
Analysis of host and symbiont phylogenetic trees did not support a history of strict cospeciation, and Symbiont-derived compounds known to defend host larvae from predation were only detected in two out of four symbiotic Bugula species. Expand
Latitudinal Variation of a Defensive Symbiosis in the Bugula neritina (Bryozoa) Sibling Species Complex
TLDR
Evidence suggests that an uncultured vertically transmitted symbiont, “Candidatus Endobugula sertula”, hosted by B. neritina produces the bryostatins, which protect the vulnerable larvae from predation, and that this host-symbiont relationship is more flexible than previously thought. Expand
Bacillus thuringiensisplasmid stability in Treadmilling of a prokaryotic tubulin-like protein , TubZ , required for data
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Lack of Overt Genome Reduction in the Bryostatin-Producing Bryozoan Symbiont “Candidatus Endobugula sertula”
TLDR
The genome assembly and transcriptome analysis for “Ca. Endobugula sertula” shed light on the metabolism of this symbiont, potentially aiding isolation and culturing efforts and suggesting that it may be able to live outside the host if its metabolic deficiencies are alleviated by medium components. Expand
Single sample resolution of rare microbial dark matter in a marine invertebrate metagenome
TLDR
This work recovered high quality genome assemblies for several rare instances of “microbial dark matter,” or phylogenetically divergent bacteria lacking genomes in reference databases, from a single tissue sample that was not subjected to any physical or chemical pre-treatment. Expand
Draft genome of Bugula neritina, a colonial animal packing powerful symbionts and potential medicines
TLDR
This dataset fills in one gap in the genome knowledge of animal phyla with a draft genome of Bugula neritina (phylum Bryozoa), as well as genes and proteins predicted de novo and verified using transcriptome data, along with the functional annotation. Expand
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