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BRD7, a novel bromodomain gene, inhibits G1–S progression by transcriptionally regulating some important molecules involved in ras/MEK/ERK and Rb/E2F pathways
  • Jie Zhou, J. Ma, +8 authors G. Li
  • Medicine, Biology
  • Journal of cellular physiology
  • 1 July 2004
Bromodomain is a 110 amino acid domain. It is evolutionally conserved and is found in proteins strongly implicated in signal‐dependent transcriptional regulation. BRD7 is a novel bromodomain gene andExpand
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Effect of SPLUNC1 protein on the Pseudomonas aeruginosa and Epstein-Barr virus
Short palate, lung and nasal epithelium clone 1 (SPLUNC1) gene coded a secreted protein found at the surface of nasopharyngeal epithelium, which may be an innate immunity defensive molecular and aExpand
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Gene expression profiling of nasopharyngeal carcinoma reveals the abnormally regulated Wnt signaling pathway.
Nasopharyngeal carcinoma (NPC) is a particularly common malignant disease in areas of south China and Southeast Asia. To characterize the gene expression profiling of NPC, we detected the geneExpand
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Differential miRNA expression and their target genes between NGX6-positive and negative colon cancer cells
Nasopharyngeal carcinoma-associated gene 6 (NGX6) was shown to be a novel putative tumor suppressor gene in colon cancer. The purpose of this study is to investigate its role in regulation of miRNAExpand
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Grade-specific expression profiles of miRNAs/mRNAs and docking study in human grade I-III astrocytomas.
  • D. Li, Pan Chen, +8 authors G. Li
  • Medicine, Biology
  • Omics : a journal of integrative biology
  • 6 October 2011
Although several miRNAs have been identified to be involved in glioblastoma tumorigenesis, little is known about the global expression profiles of miRNAs and their functional targets in astrocytomasExpand
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MiR-34b-3 and miR-449a inhibit malignant progression of nasopharyngeal carcinoma by targeting lactate dehydrogenase A
MicroRNA expression profiling assays have shown that miR-34b/c and miR-449a are down-regulated in nasopharyngeal carcinoma (NPC); however, the targets and functions of miR-34b/c and miR-449a in theExpand
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circMAN1A2 could serve as a novel serum biomarker for malignant tumors
Novel diagnostic and prognostic biomarkers of cancers are needed to improve precision medicine. Circular RNAs act as important regulators in cancers at the transcriptional and posttranscriptionalExpand
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Identification of a New Seven-span Transmembrane Protein: NGX6a Is Downregulated in Nasopharyngeal Carcinoma and Is Associated With Tumor Metastasis
  • L. Wang, B. Xiang, +5 authors G. Li
  • Medicine, Biology
  • The journal of histochemistry and cytochemistry…
  • 1 January 2010
Nasopharyngeal carcinoma (NPC)-associated gene 6 (NGX6) is a novel candidate metastasis suppressor gene that can significantly decrease the growth, motility, and invasion of NPC cells. In this study,Expand
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Effect of Freeze-Thaw on Water Stability of Aggregates in a Black Soil of Northeast China
Abstract Soil aggregate stability, an important index of the physical characteristics of a soil, can provide a good indication of a soil's erodibility, and deserves special consideration in regionsExpand
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Differential expression of Epstein-Barr virus-encoded RNA and several tumor-related genes in various types of nasopharyngeal epithelial lesions and nasopharyngeal carcinoma using tissue microarray
Studies have revealed that Epstein-Barr virus (EBV) infection, genetic aberration, and environmental factors are of importance in the development of nasopharyngeal carcinoma (NPC), although theExpand
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