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Protective effect of propionyl-L-carnitine against PAF-induced rat paw oedema.
- A. Caruso, V. Cutuli, E. de Bernardis, G. Leonardi, M. Amico-Roxas
- Chemistry, MedicinePharmacological research
PLC inhibits rat paw oedema induced by platelet activating factor (PAF), while LC and ALC, as well as indomethacin and phenylbutazone, are ineffective and it is suggested that such anti-inflammatory activity of PLC may be due to various mechanisms converging on a stabilizing action upon biomembranes.
Inhibitory effects of propionyl-L-carnitine on plasma extravasation induced by irritants in rodents.
- M. Amico-Roxas, A. Caruso, V. Cutuli, E. de Bernardis, G. Leonardi
- MedicineDrugs under experimental and clinical research
In all the tested models, L-carnitine and acetyl-L-c Carnitine were ineffective, suggesting a specific protective role of PLC in the vascular component of the inflammatory process.
Protective effects of papaverine salicylate in mouse ear dermatitis and PAF-induced rat paw oedema
- E. Bernardis, G. Leonardi, A. Caruso, V. Cutuli, M. Amico-Roxas
- Chemistry, MedicineAgents and Actions
- 1 August 1994
MR-800 exerted a dose-dependent inhibitory activity in all assays, when equimolar doses of sodium salicylate or papaverine were less effective, suggesting the existence of a favourable synergism between salicYLate and papaversine.
Effects of pharmaceuticals (Caffeine and Ibuprofen) and AMF inoculation on the growth and yield of Oryza sativa L.
Abstract Alternative water sources for crop production need to be identified in order to meet increasing food demand under climate change scenario. However unconventional water source can contain…
Studies on mouse tail infarction induced by endothelin/carrageenin
Membrane stabilizing effects of propionyl-l-carnitine:In vivo andin vitro evidences
- E. Bernardis, A. Caruso, V. Cutuli, G. Leonardi, M. Amico-Roxas, M. Alberghina
- BiologyAgents and Actions
- 1 August 1994
The results support the view that membrane stabilization and prevention of cytotoxic enzyme leakage are primarily involved in the tissue protective effect of this compound.