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Antibody stimulation of benzo(a)pyrene carcinogenesis.
Benzo(a)pyrene (BP) was conjugated to horse serum albumin (HSA) and then attached to aldehyde fixed human erythrocytes. These cells were used in a passive hemagglutination test to measure BPExpand
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Initiation-promotion skin carcinogenesis: inhibition by cyclic and non-cyclic nucleotides.
The effect of nucleotides on initiation-promotion skin carcinogenesis in Swiss mice was investigated. Cyclic AMP was given before initiation with DMBA, between initiation and promotion, and at theExpand
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Prevention of monkey sperm penetration of zona-free hamster ova by sperm antibody obtained from vasectomized cynomolgus monkeys.
Incubation of antisperm sera from vasectomized cynomolgus monkeys (Macaca fascicularis) with monkey sperm caused a fourfold reduction of sperm attachment to and penetration of zona-free GoldenExpand
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Sperm-agglutinating and -immobilizing antibody formation following vasectomy prevented with dexamethasone in cynomolgus monkeys.
Cynomolgus monkeys (Macaca fascicularis) were treated with 1.5 mg/kg dexamethasone (DEX) before (4 to 2 days) and after (0, 2, 4, and 7 days) vasectomy. Of the four monkeys treated with DEX, only oneExpand
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Adenylate Cyclase Stimulation by Trypsin
Summary Adenylate cyclase activity of a rat embryo fibroblast cell line (F111) is markedly increased by brief treatment with 1:300 trypsin. The degree of stimulation depends upon the length of timeExpand
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Prevention of autoimmunization to spermatozoa by passive antibody.
The objective of this investigation was to determine if sperm antibody formation after vasectomy in guinea pigs can be inhibited by passive administration of antiserum to spermatozoa. Sperm antibodyExpand
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Initiation-Promotion Skin Carcinogenesis and Immunological Competence 1 2 3
Summary The immune competence of mice during initiation-promotion skin carcinogenesis was determined by skin allograft rejection and lymphocyte mitogenesis. The carcinogen 7,Expand
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Skin allograft survival and lowered maternal immunologic reactivity.
Rejection of skin allografts in mice was delayed from an average of 10.5 days to 13.1 days by daily intraperitoneal injections of cortisone, and to 16.2 days by cortisone plus human chorionicExpand
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Enhancement of 7,12-dimethylbenzanthracene skin carcinogenesis by adenosine 3',5'-cyclic monophosphate.
Adenosine 3′,5′-cyclic monophosphate was injected i.p. into strain A mice receiving the chemical carcinogen 7,12-dimethylbenzanthracene topically on the interscapular area of the skin. AdenosineExpand
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Cyclic adenosine 3',5'-monophosphate and cell volume.
Summary The morphological changes in L-cells induced by cyclic adenosine 3′,5′-monophosphate (cAMP) were investigated with the scanning electron microscope and quantitated by cell volumeExpand
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