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Neurocircuitry of Addiction
Drug addiction is a chronically relapsing disorder that has been characterized by (1) compulsion to seek and take the drug, (2) loss of control in limiting intake, and (3) emergence of a negativeExpand
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Neurocircuitry of Addiction
Correction to: Neuropsychopharmacology Reviews (2010) 35, 217–238; doi:10.1038/npp.2009.110; published online 26 August 2009 In this article, there is an error in Figure 4; a revised Figure 4 isExpand
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Neurobiologic Advances from the Brain Disease Model of Addiction.
This article reviews scientific advances in the prevention and treatment of substance-use disorder and related developments in public policy. In the past two decades, research has increasinglyExpand
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Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry.
A simplified method for the quantitative analysis of neurosteroids in rat plasma and brain is described. The method uses negative chemical ionization gas chromatography/mass spectrometry and involvesExpand
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The Development and Maintenance of Drug Addiction
What is the defining property of addiction? We dust off a several-decades-long debate about the relative importance of two forms of reinforcement—positive reinforcement, subjectively linked toExpand
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Preclinical studies of alcohol binge drinking
Binge drinking is prevalent and has serious biomedical consequences. In children, adolescents, and young adults, it is a prominent risk factor for later development of alcohol‐use disorders. ManyExpand
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Sex Differences in Animal Models: Focus on Addiction
The purpose of this review is to discuss ways to think about and study sex differences in preclinical animal models. We use the framework of addiction, in which animal models have excellent face andExpand
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REVIEW: Alcohol‐related genes: contributions from studies with genetically engineered mice
Since 1996, nearly 100 genes have been studied for their effects related to ethanol in mice using genetic modifications including gene deletion, gene overexpression, gene knock‐in, and occasionallyExpand
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A molecular link between the active component of marijuana and Alzheimer's disease pathology.
Alzheimer's disease is the leading cause of dementia among the elderly, and with the ever-increasing size of this population, cases of Alzheimer's disease are expected to triple over the next 50Expand
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The Role of Corticotropin‐Releasing Factor in the Anxiogenic Effects of Ethanol Withdrawal
In summary, endogenous CRF has been demonstrated to play an important role in the endocrine but also autonomic and behavioral responses to a stressor and to mediate some of the signs and symptomsExpand
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