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Consensus Nomenclature for in vivo Imaging of Reversibly Binding Radioligands
An international group of experts in pharmacokinetic modeling recommends a consensus nomenclature to describe in vivo molecular imaging of reversibly binding radioligands.
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Blood BDNF concentrations reflect brain-tissue BDNF levels across species.
Brain-derived neurotrophic factor (BDNF) is involved in synaptic plasticity, neuronal differentiation and survival of neurons. Observations of decreased serum BDNF levels in patients withExpand
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Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport
Species differences occur in the brain concentrations of drugs, but the reasons for these differences are not yet apparent. This study was designed to compare brain uptake of three radiolabeledExpand
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The relationship between cerebral blood flow and volume in humans
The purpose of this study was to establish the relationship between regional CBF and CBV at normal, resting cerebral metabolic rates. Expand
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MR-based automatic delineation of volumes of interest in human brain PET images using probability maps
The purpose of this study was to develop and validate an observer-independent approach for automatic generation of volume-of-interest (VOI) brain templates to be used in emission tomography studies of the brain. Expand
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Cerebral Blood Flow in Patients With Chronic Heart Failure Before and After Heart Transplantation
Background and Purpose— Arterial blood pressure and cardiac output are often reduced in patients with chronic heart failure (CHF). Counterregulatory mechanisms with increased neurohormonal activationExpand
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European multicentre database of healthy controls for [123I]FP-CIT SPECT (ENC-DAT): age-related effects, gender differences and evaluation of different methods of analysis
PurposeDopamine transporter (DAT) imaging with [123I]FP-CIT (DaTSCAN) is an established diagnostic tool in parkinsonism and dementia. Although qualitative assessment criteria are available, DATExpand
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Brain serotonin 2A receptor binding: Relations to body mass index, tobacco and alcohol use
We tested in 136 healthy human subjects if body weight, alcohol intake and tobacco smoking were related to the regulation of the cerebral serotonin 2A receptor (5-HT(2A)) in humans. Expand
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Unchanged Cerebral Blood Flow and Oxidative Metabolism after Acclimatization to High Altitude
The authors investigated the effect of acclimatization to high altitude on cerebral blood flow and oxidative metabolism at rest and during exercise. Nine healthy, native sea-level residents wereExpand
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Autoregulation of Cerebral Blood Flow in Patients Resuscitated From Cardiac Arrest
Background and Purpose— Under normal circumstances, autoregulation maintains cerebral blood flow (CBF) constant within a wide range of mean arterial pressure (MAP). It remains unknown whetherExpand
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