G. Kemp

Publications438
h-index62
Citations12,664
Highly Influential Citations508
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Quantitative interpretation of bioenergetic data from 31P and 1H magnetic resonance spectroscopic studies of skeletal muscle: an analytical review.
  • G. Kemp, G. Radda
  • Chemistry, Medicine
    Magnetic resonance quarterly
  • 1 March 1994
TLDR
How to estimate the rates of glycogenolytic and aerobic ATP synthesis during exercise and oxidative ATP synthesis and proton efflux during recovery from exercise and how to assess oxidative capacity using data from steady-state exercise, work jumps, or recovery is described.
Resting-state functional connectivity in treatment-resistant depression.
TLDR
The results suggest that nonrefractory and refractory depression are characterized by distinct functional deficits in distributed brain networks.
Schwann cells, neurotrophic factors, and peripheral nerve regeneration
TLDR
This review article focuses on the roles in peripheral nerve regeneration of Schwann cells and of the neurotrophin family, CNTF and GDNF, and the relationship between these and what remains to be understood about the possible clinical use of neurotrophic factors.
Absolute quantification of phosphorus metabolite concentrations in human muscle in vivo by 31P MRS: a quantitative review
TLDR
31P MRS offers a unique view of muscle metabolism in vivo, but correct quantification of resting metabolite concentrations is important, and some consequences of uncertainty in resting [PCr] are illustrated for analysis of mitochondrial function from PCr kinetics using a published 31P M RS study of exercise and recovery.
Is depression a disconnection syndrome? Meta-analysis of diffusion tensor imaging studies in patients with MDD.
TLDR
Voxel-based analysis of DTI studies of patients with MDD consistently identified decreased fractional anisotropy in the white matter fascicles connecting the prefrontal cortex within cortical (frontal, temporal and occipital lobes) and subcortical areas (amygdala and hippocampus).
Polycystic ovary syndrome with hyperandrogenism is characterized by an increased risk of hepatic steatosis compared to nonhyperandrogenic PCOS phenotypes and healthy controls, independent of obesity…
TLDR
It is suggested that HA-PCOS is associated with hepatic steatosis, independent of obesity and insulin resistance, in women with polycystic ovary syndrome.
Physical training improves skeletal muscle metabolism in patients with chronic heart failure.
TLDR
The reduction in phosphocreatine depletion and in the increase in ADP during exercise, and the enhanced rate of phosphocreatingine resynthesis in recovery indicate that a substantial correction of the impaired oxidative capacity of skeletal muscle in chronic heart failure can be achieved by exercise training.
Quantification of skeletal muscle mitochondrial function by 31P magnetic resonance spectroscopy techniques: a quantitative review
TLDR
This work considers what can be learnt quantitatively about mitochondrial metabolism in skeletal muscle using MRS‐based methodology, and explores some technical and conceptual limitations of current methods.
Upper limb muscle imbalance in tennis elbow: A functional and electromyographic assessment
TLDR
Activation imbalance among forearm muscles (reduced extensor carpi radialis activity) in tennis elbow, probably due to protective pain‐related inhibition, could lead to a widespread upper limb muscle imbalance.
Cardiopulmonary exercise variables are associated with postoperative morbidity after major colonic surgery: a prospective blinded observational study.
TLDR
CPET variables are associated with postoperative morbidity and a multivariable model with VO₂ at θ(L) and gender discriminates those with complications after colonic surgery.
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