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Apolipoprotein J is associated with paraoxonase in human plasma.
TLDR
The specificity of the apoJ/paraoxonase interaction, inferred by the constant mole ratio of the two proteins in affinity-purified ApoJ-HDL, is confirmed in direct binding assays. Expand
Identification and characterization of novel sodium channel toxins from the sea anemone Anthopleura xanthogrammica.
TLDR
Six new toxins from the sea anemone Anthopleura xanthogrammica were identified using a molecular biological approach, and one appears to be chimera of the two previously identified 49 residue toxins native to A. xanthogramsima. Expand
Conformational and amino acid residue requirements for the saposin C neuritogenic effect.
TLDR
It is shown that the neuritogenic activity of saPOSin C requires specific placement of amino acids, and that Y30 of saposin A significantly alters local conformation in this critical region and suppresses neuritogens activity. Expand
Role for Pro-13 in directing high-affinity binding of anthopleurin B to the voltage-sensitive sodium channel.
TLDR
It is suggested that the P13V mutation results in a shift in the relative orientation of cationic residues within the large flexible loop between residues 9-18, thus strengthening their interactions with target sequences of the neuronal sodium channel. Expand