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Apolipoprotein J is associated with paraoxonase in human plasma.
TLDR
The specificity of the apoJ/paraoxonase interaction, inferred by the constant mole ratio of the two proteins in affinity-purified ApoJ-HDL, is confirmed in direct binding assays.
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Identification and characterization of novel sodium channel toxins from the sea anemone Anthopleura xanthogrammica.
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Conformational and amino acid residue requirements for the saposin C neuritogenic effect.
TLDR
It is shown that the neuritogenic activity of saPOSin C requires specific placement of amino acids, and that Y30 of saposin A significantly alters local conformation in this critical region and suppresses neuritogens activity.
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Role for Pro-13 in directing high-affinity binding of anthopleurin B to the voltage-sensitive sodium channel.
TLDR
It is suggested that the P13V mutation results in a shift in the relative orientation of cationic residues within the large flexible loop between residues 9-18, thus strengthening their interactions with target sequences of the neuronal sodium channel.
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