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Efficacy and variability of the antiproteinuric effect of ACE inhibition by lisinopril.
The antiproteinuric effect of the ACE inhibitor lisinopril appears to be dose and time related, and is strongly dependent on dietary sodium restriction, whereas it does not depend on initial proteinuria, BP, or GFR. Expand
Association between active Wegener's granulomatosis and anticytoplasmic antibodies.
- J. Tervaert, F. J. van der Woude, +7 authors T. The
- Archives of internal medicine
- 1 November 1989
Autoantibodies reacting with the cytoplasm of granulocytes and monocytes (ACPAs) were found in 42 of 45 patients with active Wegener's granulomatosis (WG) and were a specific and sensitive marker for active WG. Expand
Toward individual prognosis of IgA nephropathy.
The individual prognosis of adult IgA nephropathy patients was studied using the proportional hazards model for the time from biopsy until endstage renal disease and the estimated 5-year survival probability as predicted by the model was compared with the actual outcome. Expand
Autoantibodies against myeloid lysosomal enzymes in crescentic glomerulonephritis.
The results indicate that both vasculitis-associated CGN and idiopathic CGN are associated with autoantibodies against myeloid lysosomal enzymes, which places these disorders within one spectrum of diseases. Expand
A radioisotope method for simultaneous determination of the glomerular filtration rate and the effective renal plasma flow.
The effect of indomethacin on proteinuria and kidney function in the nephrotic syndrome.
It is proposed that the therapeutic effect of indomethacin in nephrotic syndrome is caused by its inhibiting action on renal prostaglandin synthesis, thereby potentiating the effect of the renin-angiotensin system on the kidney. Expand
Association of autoantibodies to myeloperoxidase with different forms of vasculitis.
- J. Tervaert, R. Goldschmeding, +7 authors G. K. van der Hem
- Arthritis and rheumatism
- 17 August 2010
The sensitivity of autoantibodies to MPO for either systemic necrotizing vasculitis of the polyarteritis group, WG, or idiopathic crescentic glomerulonephritis was further tested in all patients with these disorders and in selected groups of patients who had closely related diseases. Expand
Reduction of proteinuria by angiotensin converting enzyme inhibition.
It is concluded that the ACE inhibitor lisinopril effectively reduces blood pressure and proteinuria in renal disease, and is probably also due to a fall in intraglomerular capillary pressure. Expand
Diuretic Effects of Angiotensin‐Converting Enzyme Inhibition: Comparison of Low and Liberal Sodium Diet in Hypertensive Patients
- G. Navis, P. D. de Jong, A. Donker, G. K. van der Hem, D. de Zeeuw
- Journal of cardiovascular pharmacology
- 1 June 1987
The net increase in sodium excretion after enalapril administration was similar for individual patients, suggesting an individual response pattern to ACE inhibition, and may depend on initial sodium balance. Expand
Treatment of the nephrotic syndrome with indomethacin.
The results suggest that the steroid-resistant nephrotic syndrome can be treated symptomatically by indomethacin, and a harmful renal effect of long-term indomethin administration was found to be unlikely. Expand