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Molecular Docking and in Vitro Antileishmanial Evaluation of Chromene-2-thione Analogues.
Leishmaniases are an epidemic in various countries, and the parasite is developing resistance against available drugs. Thus, development of new drugs against Leishmania is an open area ofExpand
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An efficient one-pot solvent-free synthesis and photophysical properties of 9-aryl/alkyl-octahydroxanthene-1,8-diones
Abstract A facile and efficient protocol for the synthesis of 9-aryl/alkyl-3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8-octahydroxanthene-1,8-diones has been developed by one-pot reaction of dimedone withExpand
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Solvent-free sonochemical one-pot three-component synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11-triones and 1H-pyrazolo[1,2-b]phthalazine-5,10-diones
Abstract A rapid and efficient one-pot three-component protocol for the synthesis of 2 H -indazolo[2,1- b ]phthalazine-1,6,11-triones 4 and 1 H -pyrazolo[1,2- b ]phthalazine-5,10-diones 6 has beenExpand
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An efficient one-pot three-component synthesis of functionalized pyrimido[4,5-b]quinolines and indeno fused pyrido[2,3-d]pyrimidines in water
A simple, efficient, and high yielding one-pot protocol for the synthesis of pyrimido[4,5-b]quinolines and indeno[2′,1′:5,6]pyrido[2,3-d]pyrimidines has been developed by three-component dominoExpand
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Synthesis of N-functionalized/NH-multisubstituted indoles, thienopyrroles, pyrroloindoles, and pyrazolopyrroles via sequential one-pot base-mediated and copper-catalyzed inter- and intramolecular
A novel, efficient route to substituted 1-N-(het)aryl/NH-2-(het)aryl-3-cyanoindoles and related pyrrolo-fused heterocycles such as thienopyrroles, pyrroloindoles, and pyrazolopyrroles has beenExpand
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Eco-efficient, regioselective and rapid access to 4,5-disubstituted 1,2,3-thiadiazoles via [3 + 2] cycloaddition of α-enolicdithioesters with tosyl azide under solvent-free conditions
An efficient, sustainable, and regioselective one-pot synthesis of hitherto unreported 4-aroyl/hetaroyl/alkanoyl-5-alkyl/allyl/benzylsulfanyl-1,2,3-thiadiazoles has been achieved by [3 + 2]Expand
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In(OTf)3-mediated dehydrative annulation of β-ketothioamides with phenylglyoxal: one-pot access to diversely functionalized pyrrol-2-thiones
Indium triflate mediated first synthesis of diversely functionalized pyrrol-2-thiones has been developed by dehydrative annulation of β-ketothioamides with phenylglyoxal through the dominoExpand
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An expedient route to highly functionalized 2H-chromene-2-thiones via ring annulation of β-oxodithioesters catalyzed by InCl3 under solvent-free conditions
Abstract A convenient and one-pot synthesis of 3-aroyl/heteroaroyl-2H-chromene-2-thiones and benzo[f]2H-chromene-2-thiones has been developed by the condensation of β-oxodithioesters andExpand
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In(OTf)3-catalysed one-pot versatile pyrrole synthesis through domino annulation of α-oxoketene-N,S-acetals with nitroolefins.
In(OTf)3-catalyzed robust and sustainable one-pot access to previously unknown and synthetically demanding polysubstituted pyrroles via [3 + 2] annulation of α-oxoketene-N,S-acetals withExpand
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DMAP-promoted domino annulation of β-ketothioamides with internal alkynes: a highly regioselective access to functionalized 1,3-thiazolidin-4-ones at room temperature
DMAP-mediated rapid and efficient one-pot regioselective access to functionalized 1,3-thiazolidin-4-ones via annulation of β-ketothioamides with internal alkynes has been achieved under mild reactionExpand
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