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Protective effects of 3,6-dimethylamino-dibenzopyriodonium edetate on global ischemia reperfused isolated rat hearts.
The effects of 3,6-dimethylamino-dibenzopyriodonium edetate (IHC-72) on global ischemia reperfused rat hearts were investigated. In the isolated working rat heart, 40-min global ischemia followed byExpand
Effects of 3,6-dimethylamino-dibenzopyriodonium edetate on action potentials in guinea pig papillary muscles.
The effects of 3,6-dimethylamino-dibenzopyriodonium edetate (IHC-72) on action potentials (AP) and slow response action potentials of guinea pig papillary muscles were studied with intracellularExpand
Effects of IHC-72 on the ventricular muscle contraction induced by isoproterenol, calcium and histamine in guinea pigs
The effects of 3, 6(dimethylamino)-dibenzopyriodonium edetate (IHC 72) on the dose-response curves of isoproterenol, calcium and histamine in guinea-pig papillary muscles were studied. WhenExpand
[Comparison of antiarrhythmic effects of IHC-72 (an iodonium-72), lidocaine and verapamil].
The antiarrhythmic actions of 3,6-dimethylamino-dibenzopyridonium edetate (IHC-72), lidocaine (Lid) and verapamil (Ver) on several models Were compared at equitoxic doses (equal fraction of LD50).Expand
Block effects of IHC-72 on calcium current in single guinea pig cardiac myocytes.
  • G. Ji, J. Zhang
  • Chemistry, Medicine
  • Methods and findings in experimental and clinical…
  • 1 March 1994
Block of the calcium current by IHC-72 in single ventricular myocytes isolated from guinea pig was studied by using the whole-cell patch clamp technique. IHC-72 in micromolar concentrations depressedExpand