• Publications
  • Influence
VEGF inhibition and renal thrombotic microangiopathy.
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Preexisting donor-specific HLA antibodies predict outcome in kidney transplantation.
The clinical importance of preexisting HLA antibodies at the time of transplantation, identified by contemporary techniques, is not well understood. We conducted an observational study analyzing theExpand
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Complement-binding anti-HLA antibodies and kidney-allograft survival.
BACKGROUND Anti-HLA antibodies hamper successful transplantation, and activation of the complement cascade is involved in antibody-mediated rejection. We investigated whether the complement-bindingExpand
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Antibody‐Mediated Microcirculation Injury Is the Major Cause of Late Kidney Transplant Failure
In this study, the authors show that antibody-related microcirculation inflammation accounts in substantial part for renal transplant failure and importantly, regardless of the C4d status. This paperExpand
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Class IV-S versus class IV-G lupus nephritis: clinical and morphologic differences suggesting different pathogenesis.
BACKGROUND A recently proposed reclassification of lupus nephritis divides class IV (diffuse proliferative) lupus nephritis into those cases with predominantly segmental proliferative lesions (classExpand
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Significance of C4d Banff Scores in Early Protocol Biopsies of Kidney Transplant Recipients with Preformed Donor‐Specific Antibodies (DSA)
The significance of C4d‐Banff scores in protocol biopsies of kidney transplant recipients with preformed donor‐specific antibodies (DSA) has not been determined. We reviewed 157 protocol biopsiesExpand
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Membranous nephropathy and cancer: Epidemiologic evidence and determinants of high-risk cancer association.
The association between membranous nephropathy (MN) and cancer is often mentioned in textbooks but poorly substantiated, and the characteristics of cancer-associated MN are unknown. To address theseExpand
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The impact of donor-specific anti-HLA antibodies on late kidney allograft failure
Despite improvements in outcomes of renal transplantation, kidney allograft loss remains substantial, and is associated with increased morbidity, mortality and costs. Identifying the pathologicExpand
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Clinical Relevance of Preformed HLA Donor‐Specific Antibodies in Kidney Transplantation
This study analyzes the influence of preformed DSA, identified by HLA‐specific ELISA assays, on graft survival and evaluates the incidence of antibody‐mediated rejection (AMR) in patients with andExpand
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Clinical and morphological prognostic factors in membranous nephropathy: significance of focal segmental glomerulosclerosis.
BACKGROUND Progression of idiopathic membranous glomerulonephritis (IMGN) to renal insufficiency depends on various clinical and laboratory factors that have been taken into account in mostExpand
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