• Publications
  • Influence
Neuroblast ablation in Drosophila P[GAL4] lines reveals origins of olfactory interneurons.
Hydroxyurea (HU) treatment of early first instar larvae in Drosophila was previously shown to ablate a single dividing lateral neuroblast (LNb) in the brain. Early larval HU application to P[GAL4]Expand
  • 327
  • 72
  • PDF
Invertebrate Synapsins: A Single Gene Codes for Several Isoforms in Drosophila
Vertebrate synapsins constitute a family of synaptic proteins that participate in the regulation of neurotransmitter release. Information on the presence of synapsin homologs in invertebrates hasExpand
  • 398
  • 60
  • PDF
A cysteine-string protein is expressed in retina and brain of Drosophila.
Antibodies can be used to identify tissue- and stage-specifically expressed genes. A monoclonal antibody MAB ab49 from a hybridoma library screened for immunohistochemical staining in the adultExpand
  • 200
  • 17
Smell and Taste Perception in Drosophila melanogasterLarva: Toxin Expression Studies in Chemosensory Neurons
GAL4-driven targeted expression of tetanus toxin light chain (UAS-TeTxLC) in a subset of chemosensory neurons of the larval antennomaxillary complex (AMC) and pharynx causes abnormal chemosensoryExpand
  • 138
  • 16
  • PDF
A central neural circuit for experience-independent olfactory and courtship behavior in Drosophila melanogaster
We have studied the function of the major central olfactory pathway in fruit flies. Key elements of this pathway, the projection neurons (PNs), connect the antennal lobes with the lateralExpand
  • 172
  • 10
  • PDF
The Drosophila Eip78C gene is not vital but has a role in regulating chromosome puffs.
We have generated a number of chromosomal aberrations that disrupt the early-late ecdysone-induced 78C puff gene (Eip78C, ecdysone-induced protein, FlyBase name for the E78 gene of Stone and ThummelExpand
  • 46
  • 5
An invertebrate calcium-binding protein of the calbindin subfamily: protein structure, genomic organization, and expression pattern of the calbindin-32 gene of Drosophila
Antisera against vertebrate calcium-binding proteins cross-react with Drosophila nervous and muscle tissue. We have used an antiserum against carp parvalbumin to isolate from a Drosophila head cDNAExpand
  • 27
  • 3
  • PDF
The sap47 gene of Drosophila melanogaster codes for a novel conserved neuronal protein associated with synaptic terminals.
Proteins expressed specifically in neurons and transported to synaptic terminals are likely to constitute important molecular elements of nervous system function. In an effort to characterizeExpand
  • 50
  • 3
Diastolic Dysfunction in Human Cardiac Allografts is Related with Reduced SERCA2a Gene Expression
Previous studies demonstrated that impaired left ventricular (LV) relaxation in cardiac allografts limits exercise tolerance post‐transplant despite preserved systolic ejection fraction (EF). ThisExpand
  • 26
  • 2
A Novel EF-Hand Ca2+-Binding Protein is Expressed in Discrete Subsets of Muscle and Nerve Cells of Drosophila
Various Ca2+-binding proteins have been identified in vertebrate brain cells but their functions remain largely speculative (review Heizmann and Braun 1990). This is because vertebrate neurons cannotExpand
  • 4
  • 1