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Habitual dietary fibre intake influences gut microbiota response to an inulin-type fructan prebiotic: a randomised, double-blind, placebo-controlled, cross-over, human intervention study
TLDR
It is demonstrated that those with HDF intakes have a greater gut microbiota response and are therefore more likely to benefit from an inulin-type fructan prebiotic than those with LDF intakes. Expand
Inflammatory bowel disease and immunonutrition: novel therapeutic approaches through modulation of diet and the gut microbiome
TLDR
Four therapeutic strategies – probiotics, prebiotics, vitamin D and caloric restriction – that have the potential to improve and add to current IBD treatment regimens are highlighted. Expand
Interindividual variability in gut microbiota and host response to dietary interventions
TLDR
Emerging evidence suggests that interindividual variability in gut microbiota and host responsiveness exists, making it difficult to predict gut microbiome and host response to a given dietary intervention, which may have implications on the consistency of results among studies and the perceived success or true efficacy of a dietary intervention. Expand
Validity and Reproducibility of a Habitual Dietary Fibre Intake Short Food Frequency Questionnaire
TLDR
The DFI-FFQ cannot accurately quantify total habitual dietary fiber intakes, however, it is a quick, valid and reproducible tool in classifying individuals based on their habitual dietary fibre intakes. Expand
Influence of habitual dietary fibre intake on the responsiveness of the gut microbiota to a prebiotic: protocol for a randomised, double-blind, placebo-controlled, cross-over, single-centre study
TLDR
This study aims to investigate what influence differing habitual dietary fibre intakes have on the responsiveness of the gut microbiota to a prebiotic intervention. Expand
Genomic insights from Monoglobus pectinilyticus: a pectin-degrading specialist bacterium in the human colon
TLDR
This strain occupies a new ecological niche for a primary degrader specialized in foraging a habitually consumed plant glycan, thereby enriching the understanding of the diverse community profile of the HGM. Expand
Variability in gut microbiota response to an inulin-type fructan prebiotic within an in vitro three-stage continuous colonic model system
TLDR
It is demonstrated that media with different fermentable carbohydrate contents caused variability in gut microbiota responsiveness to an inulin-type fructan prebiotic; however, these results will need to be replicated in an in vitro three-stage continuous colonic model system. Expand
Fiber and Prebiotic Interventions in Pediatric Inflammatory Bowel Disease: What Role Does the Gut Microbiome Play?
TLDR
Pediatric IBD specific studies that focus on the benefits of fiber and prebiotics on gut microbiome composition and functional capacity and disease outcomes are required. Expand
Prebiotic enriched exclusive enteral nutrition suppresses colitis via gut microbiome modulation and expansion of anti-inflammatory T cells in a mouse model of colitis.
TLDR
The EEN IN group showed reduced colitis development as compared to the chow and EEN groups, which highlights the potential benefits of EEN In as a novel induction therapy for pediatric CD and UC patients. Expand
AN INULIN-TYPE FRUCTAN ENRICHED EXCLUSIVE ENTERAL NUTRITION FORMULA SUPPRESSES COLITIS THROUGH GUT MICROBIOME MODULATION AND PROMOTING EXPANSION OF ANTI-INFLAMMATORY T CELL SUBSETS
TLDR
It is demonstrated that inulin-type fructan enriched exclusive enteral nutrition formula reduced colitis development likely due to butyrate-dependent pathways that helped preserve the mucus layer and promote an anti-inflammatory intestinal environment via expansion of regulatory T cells. Expand
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