Habitual dietary fibre intake influences gut microbiota response to an inulin-type fructan prebiotic: a randomised, double-blind, placebo-controlled, cross-over, human intervention study
- G. Healey, R. Murphy, C. Butts, L. Brough, K. Whelan, J. Coad
- Medicine, BiologyBritish Journal of Nutrition
- 8 January 2018
It is demonstrated that those with HDF intakes have a greater gut microbiota response and are therefore more likely to benefit from an inulin-type fructan prebiotic than those with LDF intakes.
Inflammatory bowel disease and immunonutrition: novel therapeutic approaches through modulation of diet and the gut microbiome
- Larissa S Celiberto, F. A. Graef, B. Vallance
- Biology, MedicineImmunology
- 1 September 2018
Four therapeutic strategies – probiotics, prebiotics, vitamin D and caloric restriction – that have the potential to improve and add to current IBD treatment regimens are highlighted.
Interindividual variability in gut microbiota and host response to dietary interventions
Emerging evidence suggests that interindividual variability in gut microbiota and host responsiveness exists, making it difficult to predict gut microbiome and host response to a given dietary intervention, which may have implications on the consistency of results among studies and the perceived success or true efficacy of a dietary intervention.
Validity and Reproducibility of a Habitual Dietary Fibre Intake Short Food Frequency Questionnaire
- G. Healey, L. Brough, R. Murphy, D. Hedderley, Chrissie Butts, J. Coad
- MedicineNutrients
- 1 September 2016
The DFI-FFQ cannot accurately quantify total habitual dietary fiber intakes, however, it is a quick, valid and reproducible tool in classifying individuals based on their habitual dietary fibre intakes.
Fiber and Prebiotic Interventions in Pediatric Inflammatory Bowel Disease: What Role Does the Gut Microbiome Play?
- G. Healey, Larissa S Celiberto, Soo Min Lee, K. Jacobson
- Biology, MedicineNutrients
- 1 October 2020
Pediatric IBD specific studies that focus on the benefits of fiber and prebiotics on gut microbiome composition and functional capacity and disease outcomes are required.
Genomic insights from Monoglobus pectinilyticus: a pectin-degrading specialist bacterium in the human colon
- C. Kim, G. Healey, D. Rosendale
- BiologyThe ISME Journal
- 6 February 2019
This strain occupies a new ecological niche for a primary degrader specialized in foraging a habitually consumed plant glycan, thereby enriching the understanding of the diverse community profile of the HGM.
Influence of habitual dietary fibre intake on the responsiveness of the gut microbiota to a prebiotic: protocol for a randomised, double-blind, placebo-controlled, cross-over, single-centre study
This study aims to investigate what influence differing habitual dietary fibre intakes have on the responsiveness of the gut microbiota to a prebiotic intervention.
Prebiotic Enriched Exclusive Enteral Nutrition Suppresses Colitis via Gut Microbiome Modulation and Expansion of Anti-inflammatory T Cells in a Mouse Model of Colitis
- G. Healey, K. Tsai, K. Jacobson
- Medicine, BiologyCellular and Molecular Gastroenterology and…
- 29 June 2021
Therapeutic Advances in Gut Microbiome Modulation in Patients with Inflammatory Bowel Disease from Pediatrics to Adulthood
- Adi Eindor-Abarbanel, G. Healey, K. Jacobson
- Biology, MedicineInternational Journal of Molecular Sciences
- 1 November 2021
This review highlights important microbiome studies in patients with IBD and their response to different microbiome modulation therapies, and describes the differences in therapeutic response between pediatric and adult patient cohorts.
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