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Direct activation of the Mauthner cell by electric field pulses drives ultrarapid escape responses.
Rapid escape swims in fish are initiated by the Mauthner cells, giant reticulospinal neurons with unique specializations for swift responses. The Mauthner cells directly activate motoneurons andExpand
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A Perimotor Framework Reveals Functional Segmentation in the Motoneuronal Network Controlling Locomotion in Caenorhabditis elegans
The neuronal connectivity dataset of the nematode Caenorhabditis elegans attracts wide attention from computational neuroscientists and experimentalists. However, the dataset is incomplete. TheExpand
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C. elegans G Protein Regulator RGS-3 Controls Sensitivity to Sensory Stimuli
Signal transduction through heterotrimeric G proteins is critical for sensory response across species. Regulator of G protein signaling (RGS) proteins are negative regulators of signal transduction.Expand
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Ablation of rat TRPV1-expressing Adelta/C-fibers with resiniferatoxin: analysis of withdrawal behaviors, recovery of function and molecular correlates
BackgroundAblation of TRPV1-expressing nociceptive fibers with the potent capsaicin analog resiniferatoxin (RTX) results in long lasting pain relief. RTX is particularly adaptable to focalExpand
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Motoneurons Dedicated to Either Forward or Backward Locomotion in the Nematode Caenorhabditis elegans
Multifunctional motoneurons and muscles, which are active during forward and backward locomotion are ubiquitous in animal models. However, studies in the nematode Caenorhabditis elegans suggest thatExpand
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TOR‐mediated regulation of metabolism in aging
Cellular metabolism is regulated by the mTOR kinase, a key component of the molecular nutrient sensor pathway that plays a central role in cellular survival and aging. The mTOR pathway promotesExpand
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Neurobiology of Caenorhabditis elegans Locomotion: Where Do We Stand?
Animals use a nervous system for locomotion in some stage of their life cycle. The nematode Caenorhabditis elegans, a major animal model for almost all fields of experimental biology, has long beenExpand
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By the teeth of their skin, cavefish find their way
Summary Teeth and skin teeth (denticles), collectively named odontodes, are usually associated with the physical roles of cutting, protection or drag reduction in fishes [1,2]. These structures areExpand
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A connectivity model for the locomotor network of Caenorhabditis elegans
Recently, we described a new method for representing and analyzing the connectivity of a motoneuronal network. We used it to deduce a connectivity model for the neuromuscular network that generatesExpand
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Identification of a novel spinal nociceptive-motor gate control for Aδ pain stimuli in rats
Physiological responses to nociceptive stimuli are initiated within tens of milliseconds, but the corresponding sub-second behavioral responses have not been adequately explored in awake,Expand
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