• Publications
  • Influence
Direct activation of the Mauthner cell by electric field pulses drives ultrarapid escape responses.
TLDR
It is proposed that EFPs directly activate Mauthner cells because of their large size, thereby driving ultrarapid escape responses in fish, supported by pharmacological blockade of synaptic transmission in zebrafish.
Motoneurons Dedicated to Either Forward or Backward Locomotion in the Nematode Caenorhabditis elegans
TLDR
These are the first recordings of motoneuron activity in C. elegans and the only direction-dedicated motoneurons described to date.
A Perimotor Framework Reveals Functional Segmentation in the Motoneuronal Network Controlling Locomotion in Caenorhabditis elegans
TLDR
The perimotor framework of observed connectivity and the segmented connectivity model give insights and advance the study of the neuronal infrastructure underlying locomotion in C. elegans and suggest that the tools used may be useful to interpret, simplify, and represent connectivity data of other motor systems.
Ablation of rat TRPV1-expressing Adelta/C-fibers with resiniferatoxin: analysis of withdrawal behaviors, recovery of function and molecular correlates
TLDR
Behavioral recovery following peripheral RTX treatment is linked to regeneration of TRPV1-expressing Adelta and C-fibers and sustained expression of molecular markers and Infrared laser stimulation is a potentially valuable tool for evaluating the behavioral role of Adelta fibers in pain and pain control.
Parasitoid wasp sting: a cocktail of GABA, taurine, and beta-alanine opens chloride channels for central synaptic block and transient paralysis of a cockroach host.
TLDR
Together these data demonstrate that Ampulex utilizes GABAergic chloride channel activation as a strategy for central synaptic block to induce transient and focal leg paralysis in its host.
Direct injection of venom by a predatory wasp into cockroach brain.
TLDR
It is demonstrated that the wasp stings directly into the target ganglia in the head of its prey, the first direct evidence documenting targeted delivery of venom by a predator into the brain of its predator prey.
Wasp venom blocks central cholinergic synapses to induce transient paralysis in cockroach prey.
TLDR
The transient paralytic effect of the thoracic sting can be mainly accounted for by the presence of a venom active component that induces a postsynaptic block of central cholinergic synaptic transmission.
TOR‐mediated regulation of metabolism in aging
TLDR
The current progress in understanding the contribution of mTOR‐regulating factors to autophagy and longevity is discussed and it is suggested that conserved molecular pathways have the strongest potential for the development of new avenues for treatment of age‐related diseases.
Neurobiology of Caenorhabditis elegans Locomotion: Where Do We Stand?
TLDR
The nematode Caenorhabditis elegans is used for detailed studies of genetic and physiological locomotion mechanisms, and locomotion behavior, the parts constituting the locomotion system, and the relevant neuronal connectivity are described.
...
1
2
3
4
5
...