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- Publications
- Influence
Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.
- X. Huang, M. Cuajungco, +17 authors A. Bush
- Chemistry, Medicine
- The Journal of biological chemistry
- 24 December 1999
Oxidative stress markers as well as high concentrations of copper are found in the vicinity of Abeta amyloid deposits in Alzheimer's disease. The neurotoxicity of Abeta in cell culture has been… Expand
Psychosocial Treatments for Child and Adolescent Disorders: Empirically Based Strategies for Clinical Practice
- G. Hanson
- Medicine
- 1 February 1998
Molecular analysis of dimethyl sulphide dehydrogenase from Rhodovulum sulfidophilum: its place in the dimethyl sulphoxide reductase family of microbial molybdopterin‐containing enzymes
- C. A. McDevitt, P. Hugenholtz, G. Hanson, A. McEwan
- Biology, Medicine
- Molecular microbiology
- 1 June 2002
Dimethyl sulphide dehydrogenase catalyses the oxidation of dimethyl sulphide to dimethyl sulphoxide (DMSO) during photoautotrophic growth of Rhodovulum sulfidophilum. Dimethyl sulphide dehydrogenase… Expand
Cu(II) Potentiation of Alzheimer Aβ Neurotoxicity
- X. Huang, M. Cuajungco, +17 authors A. Bush
- Chemistry
- The Journal of Biological Chemistry
- 24 December 1999
Oxidative stress markers as well as high concentrations of copper are found in the vicinity of Aβ amyloid deposits in Alzheimer's disease. The neurotoxicity of Aβ in cell culture has been linked to… Expand
XSophe-Sophe-XeprView. A computer simulation software suite (v. 1.1.3) for the analysis of continuous wave EPR spectra.
- G. Hanson, K. Gates, C. Noble, M. Griffin, A. Mitchell, S. Benson
- Chemistry, Medicine
- Journal of inorganic biochemistry
- 1 May 2004
The XSophe-Sophe-XeprView computer simulation software suite enables scientists to easily determine spin Hamiltonian parameters from isotropic, randomly oriented and single crystal continuous wave… Expand
Pleomorphic copper coordination by Alzheimer's disease amyloid-beta peptide.
- S. Drew, C. Noble, C. Masters, G. Hanson, K. Barnham
- Chemistry, Medicine
- Journal of the American Chemical Society
- 2 January 2009
Numerous conflicting models have been proposed regarding the nature of the Cu(2+) coordination environment of the amyloid beta (Abeta) peptide, the causative agent of Alzheimer's disease. This study… Expand
Purple acid phosphatase: a journey into the function and mechanism of a colorful enzyme
- Gerhard Schenk, Gerhard Schenk, N. Mitić, G. Hanson, P. Comba
- Chemistry
- 15 January 2013
Abstract Purple acid phosphatases (PAPs) catalyze the hydrolysis of a wide range of phosphomonoester and amide substrates. These enzymes have been identified and characterized from numerous plant and… Expand
Role of semiconductivity and ion transport in the electrical conduction of melanin
- A. Mostert, B. Powell, +4 authors P. Meredith
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences
- 21 May 2012
Melanins are pigmentary macromolecules found throughout the biosphere that, in the 1970s, were discovered to conduct electricity and display bistable switching. Since then, it has been widely… Expand
Mutational analysis of the dimethylsulfoxide respiratory (dor) operon of Rhodobacter capsulatus.
- A. L. Shaw, S. Leimkuhler, W. Klipp, G. Hanson, A. McEwan
- Biology, Medicine
- Microbiology
- 1 June 1999
Four genes, dorC, dorD, dorB and dorR of the DMSO respiratory gene cluster of Rhodobacter capsulatus have been identified and sequenced. dorC encodes a pentahaem c-type cytochrome of the NirT class… Expand
Insights into Structure and Function of the Active Site of SoxAX Cytochromes*
- James R. Kilmartin, M. Maher, +5 authors U. Kappler
- Chemistry, Medicine
- The Journal of Biological Chemistry
- 18 May 2011
SoxAX cytochromes catalyze the formation of heterodisulfide bonds between inorganic sulfur compounds and a carrier protein, SoxYZ. They contain unusual His/Cys-ligated heme groups with complex… Expand