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A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration.
- G. Hageman, Don H. Anderson, R. Allikmets
- Biology, MedicineProceedings of the National Academy of Sciences…
- 17 May 2005
TLDR
An Integrated Hypothesis That Considers Drusen as Biomarkers of Immune-Mediated Processes at the RPE-Bruch's Membrane Interface in Aging and Age-Related Macular Degeneration
- G. Hageman, P. Luthert, N. V. Chong, L. V. Johnson, Don H. Anderson, R. Mullins
- BiologyProgress in Retinal and Eye Research
- 1 November 2001
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
- B. Gold, J. Merriam, R. Allikmets
- BiologyNature Genetics
- 5 March 2006
TLDR
A role for local inflammation in the formation of drusen in the aging eye.
- Don H. Anderson, R. Mullins, G. Hageman, L. V. Johnson
- Biology, MedicineAmerican journal of ophthalmology
- 1 September 2002
The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited
- Don H. Anderson, M. Radeke, L. V. Johnson
- Biology, MedicineProgress in Retinal and Eye Research
- 1 March 2010
Drusen associated with aging and age‐related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease
- R. Mullins, S. Russell, Don H. Anderson, G. Hageman
- Biology, MedicineFASEB journal : official publication of the…
- 1 May 2000
TLDR
Seven New Loci Associated with Age-Related Macular Degeneration
- L. Fritsche, Wei Chen, G. Abecasis
- BiologyNature Genetics
- 3 March 2013
TLDR
The role of inflammation in the pathogenesis of age-related macular degeneration.
- L. Donoso, David Kim, A. Frost, A. Callahan, G. Hageman
- Biology, MedicineSurvey of ophthalmology
- 1 March 2006
Age‐related macular degeneration—emerging pathogenetic and therapeutic concepts
- K. Gehrs, Don H. Anderson, L. V. Johnson, G. Hageman
- Medicine, BiologyAnnals of medicine
- 1 January 2006
TLDR
Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F.
- K. Alagramam, H. Yuan, R. Smith
- BiologyHuman molecular genetics
- 1 August 2001
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