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SPR Studies of Carbohydrate–Protein Interactions: Signal Enhancement of Low‐Molecular‐Mass Analytes by Organoplatinum(II)‐Labeling
The relatively insensitive surface plasmon resonance (SPR) signal detection of low‐molecular‐mass analytes that bind with weak affinity to a protein—for example, carbohydrate–lectin binding—isExpand
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Synthesis of (S)‐8a‐Methyl‐3,4,8,8a‐Tetrahydro‐1,6‐(2H,7H)‐Naphthalenedione via N‐tosyl‐(Sa)‐binam‐l‐prolinamide Organocatalysis
(S)-8a-Methyl-3,4,8,8a-tetrahydro-1,6(2H,7H)-naphtalenedione 2-Methyl-2-(3-oxobutyl)-1,3-cyclohexanedione 2-Methyl-1,3-cyclohexanedione N-Tosyl-(Sa)-binam-L-prolinamideExpand
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Alcohols as electrophiles in C--C bond-forming reactions: the hydrogen autotransfer process.
The hydrogen autotransfer process involves an initial oxidative hydrogen elimination, followed by different types of reactions, and is completed with a reductive hydrogen addition to give the finalExpand
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Organocatalytic enantioselective multicomponent reactions (OEMCRs)
Abstract The achieved level of expertise in organocatalytic processes has allowed synthetic chemists to apply this useful synthetic strategy to enantioselective multicomponent reactions. Although,Expand
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Enantioselective direct aldol reaction: the blossoming of modern organocatalysis
We are grateful to the Spanish Ministerio de Educacion y Ciencia, as well as to Generalitat Valenciana and University of Alicante, for their continuous financial support.
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Deep Eutectic Solvents: The Organic Reaction Medium of the Century
This microreview summarizes the use of deep eutectic solvents (DESs) and related melts in organic synthesis. Solvents of this type combine the great advantages of other proposed environmentallyExpand
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Enantioselective α-heterofunctionalisation of carbonyl compounds: organocatalysis is the simplest approach
Abstract Enantioselective organocatalytic processes have reached maturity in recent years with an impressive number of applications now available. The application of these advantageous methodologiesExpand
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A highly efficient solvent-free asymmetric direct aldol reaction organocatalyzed by recoverable (S)-binam-L-prolinamides. ESI-MS evidence of the enamine-iminium formation.
Recoverable (S(a))-binam-L-prolinamide in combination with benzoic acid is used as catalysts in the direct aldol reaction between cycloalkyl, alkyl, and alpha-functionalized ketones and aldehydesExpand
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Lipase active-site-directed anchoring of organometallics: metallopincer/protein hybrids.
The work described herein presents a strategy for the regioselective introduction of organometallic complexes into the active site of the lipase cutinase. Nitrophenol phosphonate esters, well knownExpand
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