Recent progress in synthetic and biological studies of GPI anchors and GPI-anchored proteins.
- Shi-chong Yu, Zhongwu Guo, Charles Johnson, G. Gu, Qiu-ye Wu
- Biology, ChemistryCurrent Opinion in Chemical Biology
- 1 December 2013
A novel pathway for nicotine degradation by Aspergillus oryzae 112822 isolated from tobacco leaves.
- Xiangzhou Meng, Lili Lu, G. Gu, M. Xiao
- Chemistry, BiologyResearch in Microbiology
- 1 September 2010
Efficient and Regioselective Synthesis of β-GalNAc/GlcNAc-Lactose by a Bifunctional Transglycosylating β-N-Acetylhexosaminidase from Bifidobacterium bifidum
- Xiaodi Chen, Li Xu, M. Xiao
- Chemistry, BiologyApplied and Environmental Microbiology
- 15 July 2016
A microbial β-N-acetylhexosaminidase is described that exhibited strong transglycosylation activity and strict regioselectivity for β- N- acetyl hexosaminyl lactose synthesis and thus provides a powerful synthetic tool to obtain biologically important GalNAcβ1-3Lac and GlcNAc β1-4Lac.
Synthesis and antitumor activities of glucan derivatives
- Yuguo Du, G. Gu, Y. Hua, Guohua Wei, X. Ye, Guangli Yu
- Chemistry, Biology
- 19 July 2004
Converting a β-N-acetylhexosaminidase into two trans-β-N-acetylhexosaminidases by domain-targeted mutagenesis
- Xiaodi Chen, Lan Jin, M. Xiao
- BiologyApplied Microbiology and Biotechnology
- 10 December 2019
NMR investigation of protein–substrate interaction revealed an invariable mode of the catalytic cavity of D714T, W773R, and WT BbhI, which paved the way for directed evolution by site-saturation mutagenesis of β-N-acetylhexosaminidase.
Design and comprehensive assessment of a biomimetic tri-layer tubular scaffold via biodegradable polymers for vascular tissue engineering applications.
- W. Jia, Min Li, Hongjuan Weng, G. Gu, Zonggang Chen
- Materials Science, BiologyMaterials Science and Engineering C: Materials…
- 1 May 2020
Synthetic and Immunological Studies of Mycobacterial Lipoarabinomannan Oligosaccharides and Their Protein Conjugates.
- Lizhen Wang, Shaojie Feng, Lian An, G. Gu, Zhongwu Guo
- Chemistry, BiologyJournal of Organic Chemistry
- 29 September 2015
A convergent strategy was developed for the synthesis of LAM oligosaccharides with an α-1,2-linked dimannopyranose cap at the nonreducing end, verifying the potential of the oligosACcharides for vaccine development and other immunological studies.
Hyaluronic acid oligosaccharide-modified collagen nanofibers as vascular tissue-engineered scaffold for promoting endothelial cell proliferation.
- Lingzhi Kang, W. Jia, Zonggang Chen
- Biology, EngineeringCarbohydrate Polymers
- 1 November 2019
Fabrication and Comprehensive Characterization of Biomimetic Extracellular Matrix Electrospun Scaffold for Vascular Tissue Engineering Applications
- W. Jia, Min Li, Lingzhi Kang, G. Gu, Zhongwu Guo, Zonggang Chen
- Materials Science, BiologyJournal of Materials Science
- 1 August 2019
The results indicate that the biomimetic matrix collagen–HA electrospun nanofibrous scaffold could promote PIECs proliferation and may be a better candidate with endothelial potential for the vascular tissue-engineered inner-layer scaffold.
Synthesis of novel galactose containing chemicals by beta-galactosidase from Enterobacter cloacae B5.
- Lili Lu, Xiaodong Xu, G. Gu, Lan Jin, M. Xiao, Fengshan Wang
- Chemistry, BiologyBioresource Technology
- 1 September 2010
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