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- Publications
- Influence
Acute SSRI Administration Affects the Processing of Social Cues in Healthy Volunteers
- C. Harmer, Z. Bhagwagar, D. Perrett, B. Völlm, P. Cowen, G. Goodwin
- Psychology, Medicine
- Neuropsychopharmacology
- 2003
Enhancement of serotonin neurotransmission plays an important role in the antidepressant response to agents presently available to treat depression. This response forms the major evidence for the… Expand
A single dose of citalopram increases fear recognition in healthy subjects
- M. Browning, C. Reid, P. Cowen, G. Goodwin, C. Harmer
- Medicine, Psychology
- Journal of psychopharmacology
- 15 April 2007
We have previously shown that a single dose of intravenous citalopram in healthy volunteers enhances the detection of fearful facial expressions, suggesting an effect of acute selective serotonin… Expand
Gender differences in the relationship between personality dimensions and relative body weight.
- M. Faith, J. Flint, C. Fairburn, G. Goodwin, D. Allison
- Psychology, Medicine
- Obesity research
- 1 October 2001
OBJECTIVE
The relationship between body mass index (BMI: kg/m(2)) and personality seems to differ for men and women, although these effects may be driven by the extremes of the BMI distribution. It… Expand
Erythropoietin Improves Mood and Modulates the Cognitive and Neural Processing of Emotion 3 Days Post Administration
- K. Miskowiak, B. Inkster, S. Selvaraj, R. Wise, G. Goodwin, C. Harmer
- Psychology, Medicine
- Neuropsychopharmacology
- 1 February 2008
Erythropoietin (Epo) has neuroprotective and neurotrophic effects and is a promising candidate for treatment of neurodegenerative and psychiatric disorder. Recently, we demonstrated that Epo… Expand
Single-photon emission computed tomography with 99mTc-exametazime in unmedicated schizophrenic patients.
- Klaus P. Ebmeier, D. Blackwood, +6 authors G. Goodwin
- Psychology, Medicine
- Biological psychiatry
- 1993
We examined 20 actively psychotic unmedicated schizophrenic patients and 20 matched control subjects by using single-photon emission, computed tomography (SPECT) with 99mtechnetium-exametazime.… Expand
Hypoactivation of the Ventral and Dorsal Striatum During Reward and Loss Anticipation in Antipsychotic and Mood Stabilizer-Naive Bipolar Disorder
- S. Yip, P. Worhunsky, R. Rogers, G. Goodwin
- Psychology, Medicine
- Neuropsychopharmacology
- 2015
Increased activity within known reward-processing neurocircuitry (eg, ventral striatum, VS) has been reported among medicated individuals with bipolar disorder (BD) I and II. However, such findings… Expand
Regional cerebral blood flow in IDDM patients: Effects of diabetes and of recurrent severe hypoglycaemia
- Dr. K. M. MacLeod, D. Hepburn, +4 authors B. Frier
- Medicine
- Diabetologia
- 1 March 1994
SummaryChronic hyperglycaemia and recurrent severe hypoglycaemia have both been implicated as causing cerebral damage in patients with diabetes. Although cognitive dysfunction and intellectual… Expand
Erythropoietin has no effect on hippocampal response during memory retrieval 3 days post-administration
- K. Miskowiak, B. Inkster, S. Selvaraj, G. Goodwin, C. Harmer
- Medicine
- Psychopharmacology
- 13 August 2007
Erythropoietin (Epo) is a primary regulator of erythropoiesis in the haematopoietic system. In addition, Epo has neuroprotective and neurotrophic effects in experimental brain damage (Brines et al.… Expand
Agomelatine facilitates positive versus negative affective processing in healthy volunteer models
- C. Harmer, C. de Bodinat, +5 authors G. Goodwin
- Psychology, Medicine
- Journal of psychopharmacology
- 1 September 2011
Agomelatine is a new antidepressant with a novel profile of pharmacological action. The clinical efficacy of agomelatine has been established in major depression, but its actions on emotional bias… Expand
Using an Experimental Medicine Model to Explore Combination Effects of Pharmacological and Cognitive Interventions for Depression and Anxiety
- M. Browning, M. Grol, Verena Ly, G. Goodwin, Emily A. Holmes, C. Harmer
- Psychology, Medicine
- Neuropsychopharmacology
- 10 August 2011
Selective serotonergic reuptake inhibitors (SSRIs) and cognitive therapies are effective in the treatment of anxiety and depression. Previous research suggests that both forms of treatments may work… Expand