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Effect of Rosuvastatin on Warfarin Pharmacodynamics and Pharmacokinetics
TLDR
It is indicated that rosuvastatin can enhance the anticoagulant effect of warfarin and Appropriate monitoring of the international normalized ratio is indicated when this drug combination is coadministered.
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Effect of renal impairment on the pharmacokinetics of PD 0200390, a novel ligand for the voltage-gated calcium channel alpha-2-delta subunit.
TLDR
PD 0200390 pharmacokinetic parameters vary predictably with decreases in renal function; therefore dose adjustment may be required in individuals with RI.
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Lack of effect of H2-receptor antagonists on the pharmacokinetics of alcohol consumed after food at lunchtime.
TLDR
None of the H2-receptor antagonists had any statistically significant effects on any of the pharmacokinetic parameters for alcohol in an open, four-way cross-over study.
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