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Allergic reactions to betalactams: studies in a group of patients allergic to penicillin and evaluation of cross‐reactivity with cephalosporin

The results indicate the relevance of side‐chain‐specific minor determinants in betalactams allergy and provide support for the role of this chemical structure in the evaluation of cross‐reactivity between penicillins and cephalosporins.
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Study of hypersensitivity reactions and anaphylaxis during anesthesia in Spain.

The results show that those drugs involved in the reaction as the etiological agent, such as antibiotics and nonsteroidal anti-inflammatory agents, can be used again outside the context of surgery.
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Acute pancreatitis caused by allergy to kiwi fruit

The kiwi (Actinidia chinensis) belongs to the Actinidiaceae family and has been known for many years to provoke acute pancreatitis experimentally in dogs after inducing anaphylactic shock.
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MRGPRX2-mediated mast cell response to drugs used in perioperative procedures and anaesthesia

MRGPRX2 is a candidate for consideration in non-IgE-mediated allergic reactions to some perioperative drugs, reinforcing its role in mast cell responses and their pathophysiology.
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Practical Guidelines for Perioperative Hypersensitivity Reactions.

A systematic review of the available scientific evidence is presented and general guidelines for the management of acute episodes and for referral of patients with perioperative hypersensitivity reactions to allergy units are provided.
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Adjuvants for allergy immunotherapeutics

This review deals with the use of adjuvants to reduce the undesirable side effects associated with specific allergen immunotherapy, and nanoparticles used as immunoadjuvants are offering promising results in preclinical assays.
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Fixed‐drug eruption due to metronidazole with positive topical provocation

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Early skin testing is effective for diagnosis of hypersensitivity reactions occurring during anesthesia

Early allergological study is useful, could minimize false negatives, but should be considered as a complement to late skin tests.
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Allergic contact dermatitis from mercury antiseptics and derivatives: study protocol of tolerance to intramuscular injections of thimerosal.

Vaccination with thimerosal is relatively safe, even for individuals with delayed type hypersensitivity to this chemical, since more than 90% of allergic patients tolerated intramuscular challenge tests withThimerosal.
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Comparable actions of omalizumab on mast cells and basophils

Omalizumab is equally and rapidly effective against autoimmune and non‐autoimmune urticaria, suggesting the possible involvement of additional mechanisms of IgE.
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