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Destructive and Protective Roles of Cytokines in Periodontitis: A Re-appraisal from Host Defense and Tissue Destruction Viewpoints
  • G. Garlet
  • Biology, Medicine
  • Journal of dental research
  • 25 August 2010
Periodontal diseases (PD) are chronic infectious inflammatory diseases characterized by the destruction of tooth-supporting structures, being the presence of periodontopathogens required, but notExpand
Chemokines in Oral Inflammatory Diseases: Apical Periodontitis and Periodontal Disease
The inflammatory oral diseases are characterized by the persistent migration of polymorphonuclear leukocytes, monocytes, lymphocytes, plasma and mast cells, and osteoblasts and osteoclasts. In theExpand
Cytokine expression pattern in compression and tension sides of the periodontal ligament during orthodontic tooth movement in humans.
Orthodontic tooth movement is achieved by the remodeling of periodontal ligament (PDL) and alveolar bone in response to mechanical loading and is believed to be mediated by several host mediators,Expand
Review of osteoimmunology and the host response in endodontic and periodontal lesions
Abstract Both lesions of endodontic origin and periodontal diseases involve the host response to bacteria and the formation of osteolytic lesions. Important for both is the upregulation ofExpand
Evidence of the presence of T helper type 17 cells in chronic lesions of human periodontal disease.
INTRODUCTION Periodontal disease is a chronic inflammation of the attachment structures of the teeth, triggered by potentially hazardous microorganisms and the consequent immune-inflammatoryExpand
Factors involved in the T helper type 1 and type 2 cell commitment and osteoclast regulation in inflammatory apical diseases.
INTRODUCTION Periapical chronic lesion formation involves activation of the immune response and alveolar bone resorption around the tooth apex. However, the overall roles of T helper type 1 (Th1),Expand
The broad effects of the functional IL‐10 promoter‐592 polymorphism: modulation of IL‐10, TIMP‐3, and OPG expression and their association with periodontal disease outcome
Periodontal diseases are infectious diseases, in which periodontopathogens trigger chronic inflammatory and immune responses that lead to tissue destruction. It occurs through the generation ofExpand
Association of IL1 gene polymorphisms with chronic periodontitis in Brazilians.
UNLABELLED Chronic periodontal disease (PD) is an infectious immune-inflammatory illness. Polymorphisms in IL1 genes play a role in inflammatory diseases through the modulation of cytokine levels. Expand
Characterization of CD4+CD25+ natural regulatory T cells in the inflammatory infiltrate of human chronic periodontitis
Periodontitis is an infectious disease, where putative periodontopathogens trigger chronic inflammatory and immune responses against periodontal structures, in which an unbalanced host response isExpand
Patients with oral squamous cell carcinoma are characterized by increased frequency of suppressive regulatory T cells in the blood and tumor microenvironment
Oral squamous cell carcinoma (OSCC) is a cancerous lesion with high incidence worldwide. The immunoregulatory events leading to OSCC persistence remain to be elucidated. Our hypothesis is thatExpand
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