Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
- Qun Li, X. Guan, Zijian Feng
- MedicineNew England Journal of Medicine
- 29 January 2020
There is evidence that human-to-human transmission has occurred among close contacts since the middle of December 2019 and considerable efforts to reduce transmission will be required to control outbreaks if similar dynamics apply elsewhere.
A Novel Coronavirus from Patients with Pneumonia in China, 2019
- N. Zhu, Dingyu Zhang, W. Tan
- Biology, MedicineNew England Journal of Medicine
- 24 January 2020
Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily, which is the seventh member of the family of coronaviruses that infect humans.
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
- R. Lu, Xiang-rong Zhao, W. Tan
- BiologyThe Lancet
- 30 January 2020
Guidelines for the use and interpretation of assays for monitoring autophagy
- D. Klionsky, F. Abdalla, Shengzhou or sheng-zhou wu
- BiologyAutophagy
- 1 April 2012
These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Human infection with a novel avian-origin influenza A (H7N9) virus.
Novel reassortant H7N9 viruses were associated with severe and fatal respiratory disease in three patients, and all three patients died.
Emergence of Fatal PRRSV Variants: Unparalleled Outbreaks of Atypical PRRS in China and Molecular Dissection of the Unique Hallmark
- K. Tian, Xiuling Yu, G. Gao
- MedicinePLoS ONE
- 13 June 2007
This is the first comprehensive report documenting the 2006 epidemic of atypical PRRS outbreak in China and identifying the 30 amino-acid deletion in NSP2, a novel determining factor for virulence which may be implicated in the high pathogenicity of PRRSV, and will stimulate further study by using the infectious cDNA clone technique.
The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
- Haitao Yang, Maojun Yang, Z. Rao
- Chemistry, BiologyProceedings of the National Academy of Sciences…
- 29 October 2003
This series of crystal structures, which is the first, to the authors' knowledge, of any protein from the SARS virus, reveal substantial pH-dependent conformational changes, and an unexpected mode of inhibitor binding, providing a structural basis for rational drug design.
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