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STUDIES OF OPPORTUNISTIC FUNGI: I. INHIBITION OF RHIZOPUS ORYZAE BY HUMAN SERUM
  • G. Gale, A. Welch
  • Medicine
  • The American journal of the medical sciences
  • 1 May 1961
Effect of chelate treatments on kidney, bone and brain lead levels of lead-intoxicated mice.
TLDR
An examination of published data describing the effect of chelating agent treatment onbrain lead levels indicates that DMSA produces a reduction in brain lead levels under all conditions examined to date. Expand
Binding of an antitumor platinum compound to cells as influenced by physical factors and pharmacologically active agents.
TLDR
Theantitumoreffectiveness ofds-Ptll2 againstavariety ofanimalneoplasms is well established(8,12,13,16,17,19,21), andclinicaltrials have beenconducted atseveralinstitutions(2,7,14,20). Expand
Antimicrobial properties of pyrrole derivatives.
Reduction of the renal toxicity of cis-dichlorodiammineplatinum(II) by probenecid.
Probenecid, when administered sc to F344 rats 1 hour prior to an iv LD50 dose of cis-dichlorodiammineplatinum(II) (CDPP), reduced significantly the peak BUN and serum creatinine levels which occurredExpand
Studies of cross-resistance, synergistic combinations and blocking of activity of platinum derivatives
Summary Certain 1,2-diamino saturated cyclic platinum derivatives have a high degree of activity against transplanted mouse leukemias and show no cross-resistance to DDP. DDP and these cyclicExpand
Effects of cis-diamminedichloroplatinum (NSC 119875) on murine and human hemopoietic precursor cells.
TLDR
When murine cells from normal and actively regenerating marrows were exposed to cis-diamminedichloroplatinum in culture, washed free of the agent, and assayed for the surviving hemopoietic precursor cells, similar sensitivity curves were obtained, indicating the absence of cell-cycle dependency of cis- diaminedich chloroplatinum. Expand
Cadmium mobilization in vivo by intraperitoneal or oral administration of monoalkyl esters of meso-2,3-dimercaptosuccinic acid in the mouse.
TLDR
The monoisoamyl ester was the most effective in removing cadmium from both the liver and the kidneys when given orally and is the first compound which is reported capable of mobilizing Cadmium in vivo from aged deposits after oral administration. Expand
Further evaluation of diethyldithiocarbamate as an antagonist of cisplatin toxicity.
N,N-disubstituted dithiocarbamates as cadmium antagonists: N-(4-methoxybenzyl)-N-dithiocarboxy-D-glucamine.
TLDR
An in-vitro assessment of the interaction of MeOBDCG, BDCG and N-methyl-N-dithiocarboxy-D-glucamine with murine Cadmium-metallothionein revealed a direct relationship between the extent of cadmium depletion from Cd-MT and the relative in- vivo efficacies of the 3 analogs. Expand
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