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Summary statement from a workshop on asymptomatic primary hyperparathyroidism: a perspective for the 21st century.
TLDR
Department of Medicine, Columbia University College of Physicians and Surgeons (J.P.B., S.J.N.), Boston, Massachusetts 02114; Department of Surgery, Duke University Medical Center (S.A.W.), Durham, North Carolina 27710.
IOF position statement: vitamin D recommendations for older adults
This position paper of the International Osteoporosis Foundation makes recommendations for vitamin D nutrition in elderly men and women from an evidence-based perspective.
Hypovitaminosis D in Healthy Schoolchildren
TLDR
The inverse changes in parathyroid hormone suggest that insufficient vitamin D levels may deleteriously affect skeletal metabolism in healthy adolescents, calling for a reconsideration of vitamin D supplementation in high-risk adolescents to further optimize skeletal health.
Hypovitaminosis D in developing countries—prevalence, risk factors and outcomes
TLDR
Clinical trials to assess the effect of vitamin D supplementation on classical and nonclassical clinical outcomes in developing countries are needed.
Hypovitaminosis D in the Middle East and North Africa
TLDR
The lack of populations based studies, gaps in studies in infants, pre-pubertal children and pregnant women, hinder the development of region specific guidelines and constitute a major obstacle to impact this chronic and most often subclinical disease.
Calcium and bone disorders during pregnancy and lactation.
Geographic and ethnic disparities in osteoporotic fractures
TLDR
Improvements in fracture assessment, in particular for nonhip fractures, and identification of factors that contribute to this variability might substantially influence the understanding of osteoporotic fracture aetiology and provide new avenues for prevention.
Secular Trends in Hip Fractures Worldwide: Opposing Trends East Versus West
TLDR
Data presented here show close parallels between rising rates of urbanization and hip fractures across disparate geographic locations and cultures.
Vitamin D: a growing perspective.
TLDR
The evidence indicates that 5 microg (200 IU)/day of vitamin D has little effect on vitamin D status as measured by the serum 25(OH)D concentration beyond infancy, and two randomized clinical trials show that higher vitamin D intake improves one-year gain in bone density in adolescent girls.
Vitamin D Deficiency in the Middle East and its Health Consequences for Children and Adults
TLDR
Suggestions for vitamin D replacement doses based on evidence available to-date are provided, as Hypovitaminosis D is a major public health problem across all life stages in the Middle East with deleterious immediate and latent manifestations and long term strategies should include public education, national health policies for screening and prevention through food fortification, and treatment through vitamin D supplementation.
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