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Alternative pathways of carbon dioxide fixation: insights into the early evolution of life?
  • G. Fuchs
  • Biology, Medicine
  • Annual review of microbiology
  • 22 September 2011
Five alternative autotrophic pathways exist in prokaryotes that differ fundamentally from the Calvin-Benson cycle and reveal that the formation of an activated acetic acid from inorganic carbon represents the initial step toward metabolism. Expand
Microbial degradation of aromatic compounds — from one strategy to four
These strategies are based on different ring activation mechanisms that consist of either formation of a non-aromatic ring-epoxide under oxic conditions, or reduction of the aromatic ring under anoxic conditions using one of two completely different systems. Expand
Autotrophic carbon fixation in archaea
The diverse carbon fixation mechanisms that are found in archaea differ fundamentally from those of the well-known Calvin cycle, and their distribution mirrors the phylogenetic positions of the archaeal lineages and the needs of the ecological niches that they occupy. Expand
A 3-Hydroxypropionate/4-Hydroxybutyrate Autotrophic Carbon Dioxide Assimilation Pathway in Archaea
The Global Ocean Sampling database contains half as many 4-hydroxybutyryl-CoA dehydratase sequences as compared with those found for another key photosynthetic CO2-fixing enzyme, ribulose-1,5-bisphosphate carboxylase-oxygenase, indicating the importance of this enzyme in global carbon cycling. Expand
Anaerobic metabolism of aromatic compounds via the benzoyl‐CoA pathway
Aromatic compounds are important growth substrates for microorganisms. They form a large group of diverse compounds including lignin monomers, amino acids, quinones, and flavonoids. Aerobic aromaticExpand
Synthesis of C5-dicarboxylic acids from C2-units involving crotonyl-CoA carboxylase/reductase: The ethylmalonyl-CoA pathway
For methylotrophic bacteria such as Methylobacterium extorquens, extension of the serine cycle with reactions of the ethylmalonyl-CoA pathway leads to a simplified scheme for isocitrate lyase-independent C1 assimilation. Expand
Bacterial phenylalanine and phenylacetate catabolic pathway revealed
This work elucidates the catabolic pathway functioning in 16% of all bacteria whose genome has been sequenced, including Escherichia coli and Pseudomonas putida, and provides insight into the natural remediation of man-made environmental contaminants such as styrene. Expand
Evidence that anaerobic oxidation of toluene in the denitrifying bacterium Thauera aromatica is initiated by formation of benzylsuccinate from toluene and fumarate.
A hypothetical degradation pathway for the anaerobic oxidation of toLUene to benzoyl-CoA via an initial addition of fumarate to the methyl group of toluene and following beta-oxidation of the benzylsuccinate formed is suggested. Expand
Phylogenetic and metabolic diversity of bacteria degrading aromatic compounds under denitrifying conditions, and description of Thauera phenylacetica sp. nov., Thauera aminoaromatica sp. nov., and
The highly varied substrate spectra of the isolates indicates that an even higher diversity of denitrifying bacteria degrading aromatic compounds would be discovered in the different habitats by using a larger spectrum of aromatic substrates for enrichment and isolation. Expand
Identifying the missing steps of the autotrophic 3-hydroxypropionate CO2 fixation cycle in Chloroflexus aurantiacus
The enigmatic disproportionation of glyoxylate and propionyl-CoA into acetyl- CoA and pyruvate is solved in an elegant and economic way requiring only 3 additional enzymes. Expand