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[Improvement of the solubility behavior of problem drugs. 20. The effect of pharmaceutical excipients on the wetability of iomeglamic acid].
From sugar beet molasses to Lyphan. Integrated quality management from the raw material to the drug.
The enzyme mechanism and specificity and the individual process-parameters for the biotransformation procedure are explained as well as the purification process of educts and products. Expand
From Sugar Beet Molasses to Lyphan
L-tryptophan is produced at the AMINO GmbH (Frellstedt, FRG) via biocatalytical condensation of the amino acid L-serine with indole. As a biocatalyst, tryptophan synthetase is used which is produced… Expand
[Improvement of the dissolution behavior of problem drugs. 11. DTA iomeglamic-PVP 25 copreciptates].
valeric acid using 5- (1,2-Dithiolan-3-yl) or their physiologically acceptable salts for the treatment of disorders of lipid metabolism
Using at least one effector of the glutathione metabolism together with alpha-lipoic acid for immunomodulatory, defense-increasing and / or anti-inflammatory treatment
Use of α-lipoic acid or their physiologically acceptable salts for the treatment of hypercholesterolemia LDL
Using 5- (1,2-Dithiolan-3-yl) valeric acid (α-lipoic acid) or their physiologically acceptable salts for the treatment of the combined LDL hypercholesterolemia (LDL> 4.14, triglycerides> 2.2 mmol /… Expand
Medicaments containing Ambroxol, its salts and / or prodrugs together with α-lipoic acid in the context of the treatment of diabetes mellitus
Arzneimittel enthaltend Ambroxol, dessen Salze und/oder dessen Prodrugs zusammen mit α-Liponsaure, deren Salze und/oder deren Prodrugs als Kombinationspraparat zur gleichzeitigen, getrennten oder… Expand
Use of an in vitro absorption model system for predicting sustained release of verapamil.
- R. Neubert, F. Fahr, C. Mäder, L. Lücke, G. Fries, G. Rostock
- Chemistry, Medicine
- 1 September 1992
It is shown that it is possible to characterize sustained release formulations in vitro using not only dissolution data but also an absorption model system. The mean dissolution time (MDT) has been… Expand
[The improvement of solubility behavior of problem drugs. 14. Effect of properties of methylcellulose-coprecipitates on solubility].