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Structure and Physicochemical Properties of Adriamycin (Doxorubicin)
Adriamycin (synonym doxorubicin) is a glycoside antibiotic whose structure and stereochemistry are represented in Fig. 1 (formula I). It consists of the tetracyclic quinoid aglycone adriamycinone
Cephem sulfones as inactivators of human leukocyte elastase. 5. 7 alpha-Methoxy- and 7 alpha-chloro-1,1-dioxocephem 4-ketones.
TLDR
A lipophilic cephem sulfone apparently able to inactivate the enzyme in living cells was identified, and double substitution with heterocyclic thiols produced compounds with diverging properties.
Axenomycins. 11. The structure of axenolide.
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