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Polyhydroxylated alkaloids -- natural occurrence and therapeutic applications.
Iminosugars as therapeutic agents: recent advances and promising trends.
The field of iminosugars continues to open up exciting new opportunities for therapeutic agent discovery and offers many new tools for precisely modifying carbohydrate structures and modulating glycosidase activity in vivo.
Sugar‐Mimic Glycosidase Inhibitors: Natural Occurrence, Biological Activity, and Prospects for Therapeutic Application
Sugar-mimic glycosidase inhibitors: natural occurrence, biological activity and prospects for therapeutic application
Glycosidase inhibition by plant alkaloids which are structural analogues of monosaccharides
Australine and related alkaloids: easy structural confirmation by 13C NMR spectral data and biological activities
Casuarine: A very highly oxygenated pyrrolizidine alkaloid
Polyhydroxylated pyrrolidines from sugar lactomes: Synthesis of 1,4-dideoxy-1,4-imino-d-glucitol from d-galactonolactone and syntheses of 1,4-dideoxy-1,4-imino-d-allitol,…
Synthetic Chemical Inducers and Genetic Decoupling Enable Orthogonal Control of the rhaBAD Promoter.
L-Mannose was found to be the most useful orthogonal inducer, providing an even greater range of induction than the native inducer l-rhamnose, and crucially, allowing sustained induction instead of transient induction.