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Infections in patients with cirrhosis increase mortality four-fold and should be used in determining prognosis.
BACKGROUND & AIMS A staged prognostic model of cirrhosis based on varices, ascites, and bleeding has been proposed. We analyzed data on infections in patients with cirrhosis to determine whether itExpand
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Adrenocortical dysfunction in liver disease: A systematic review
In patients with cirrhosis, adrenal insufficiency (AI) is reported during sepsis and septic shock and is associated with increased mortality. Consequently, the term “hepato‐adrenal syndrome” wasExpand
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Renal failure and cirrhosis: a systematic review of mortality and prognosis.
BACKGROUND & AIMS To evaluate renal failure (RF) in cirrhosis to determine and quantify its prognostic significance. METHODS Studies were identified by MEDLINE, EMBASE, Cochrane, ISI Web of ScienceExpand
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Assessment of adrenocortical reserve in stable patients with cirrhosis.
BACKGROUND & AIMS Adrenal insufficiency (AI) is reported in critically ill patients with cirrhosis and is associated with increased mortality. It is unclear if AI is an underlying condition orExpand
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Critical illness-related corticosteroid insufficiency in patients with cirrhosis and variceal bleeding.
BACKGROUND & AIMS Relative adrenal insufficiency (AI) occurs in patients with cirrhosis with sepsis, but not with variceal bleeding. We evaluated adrenal function in cirrhotic patients with andExpand
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Cardiovascular dysfunction in patients with liver cirrhosis
Hyperdynamic syndrome is a well-known clinical condition found in patients with cirrhosis and portal hypertension, characterized by increased heart rate and cardiac output, and reduced systemicExpand
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Familial frontotemporal dementia associated with the novel MAPT mutation T427M
Sirs: Mutations of the microtubule-associated protein tau (MAPT) lead to a clinically heterogeneous disorder called “Frontotemporal dementia and parkinsonism linked to chromosome 17” (FTDP-17) [1–4].Expand
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Which matters most: Number of tumors, size of the largest tumor, or total tumor volume?
Received February 14, 2011; accepted May 9, 2011.Liver transplantation for hepatocellular carcinoma(HCC) and cirrhosis is complicated by the prognosis ofboth diseases. Although there is reasonableExpand
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Comparison of total cortisol, free cortisol, and surrogate markers of free cortisol in diagnosis of adrenal insufficiency in patients with stable cirrhosis.
BACKGROUND & AIMS Measurements of serum levels of total cortisol can overestimate the prevalence of adrenal dysfunction in patients with cirrhosis because they have low concentrations ofExpand
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Propylthiouracil for alcoholic liver disease.
BACKGROUND Randomised clinical trials have addressed the question whether propylthiouracil has any beneficial effects in patients with alcoholic liver disease. OBJECTIVES To assess the beneficialExpand
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