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Increased contractility and calcium sensitivity in cardiac myocytes isolated from endurance trained rats.
TLDR
It is suggested that physical exercise induces adaptive hypertrophy in cardiac myocytes with improved contractile function after intensity controlled aerobic endurance training in the rat, and higher myofilament Ca2+ sensitivity is the dominant effect responsible for enhanced myocyte contractility in TR. Expand
Cardiomyocyte contractility and calcium handling partially recover after early deterioration during post-infarction failure in rat.
TLDR
Whereas initial deterioration of cardiac function is associated with reduced cardiomyocyte contractile function, chronic heart failure progression is not accompanied by further impairment of intrinsic cardiomeocyte contractility in this model. Expand
Effects of Cariporide and Losartan on Hypertrophy, Calcium Transients, Contractility, and Gene Expression in Congestive Heart Failure
TLDR
Losartan has salutary effects on postinfarction remodeling and gene expression, whereas cariporide is neutral, and improve cardiomyocyte contractility and calcium regulation in chronic heart failure. Expand
Cardiac contractile function and electrolyte regulation during hyperosmolal stress: an experimental study in the isolated rabbit heart.
TLDR
The results suggest that the Na+/H+ antiporter is activated on hyperosmolal exposure with a secondary activation of theNa+/K(+)-ATPase. Expand
Hyperosmotic perfusion of the beating rat heart and the role of the Na+/K+/2CI− co-transporter and the Na+/H+ exchanger
TLDR
TheNa+/H+ exchanger, but not the Na+/K+/2CI− co-transporter, is of importance in contractile recovery and electrolyte regulation during hyperosmotic perfusion in the rat heart. Expand
Identification and regulation of the gastric H+/K+-ATPase in the rat heart.
TLDR
The gastric isoform of H+/K+-ATPase is expressed in rat cardiac myocytes, both at transcript and protein levels, and functional studies indicate that the enzyme could contribute to potassium and pHi regulation in cardiomyocytes. Expand
Biophysical factors and contractile function during coronary bolus perfusion: an experimental study in the isolated guinea pig heart.
TLDR
An increase in osmolality attenuates the increased contractility induced by a purely nonionic medium and a viscosity-induced rise in perfusion pressure may increase contractility. Expand
Sodium-Calcium Relationships and Cardiac Function during Coronary Bolus Perfusion
TLDR
The present review deals with the side-effects of contrast media (CM) on cardiac function during coronary angiography and redefines existing concepts of CM osmotoxicity and chemotoxicity in terms of osmolal, ionic and molecular effects. Expand
Hyperosmotic pretreatment reduces infarct size in the rat heart.
TLDR
The results indicate that short-lasting hyperosmotic perturbations of the extracellular environment may precondition the heart to a subsequent ischemic insult. Expand
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