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Activity of serotonin-containing neurons in the nucleus raphe pallidus of freely moving cats
Serotonergic neurons within nucleus raphe pallidus (NRP) of freely moving cats initially were distinguished by their slow (less than 8 Hz), regular discharge and long duration (mean = 2.3 ms) actionExpand
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Behavioral correlates of dopaminergic unit activity in freely moving cats
Single unit activity of dopaminergic neurons in the substantia nigra was recorded in freely moving cats under a variety of conditions. These neurons displayed their highest discharge rate duringExpand
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Antagonism of the discriminative stimulus effects of the kappa-opioid agonist spiradoline
This study compared the potency of mixed-action opioids (i.e., agonist-antagonists) and pure antagonists to block the discriminative stimulus effects of spiradoline, a kappa-opioid agonist. Rats wereExpand
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Chloral hydrate anesthesia alters the responsiveness of central serotonergic neurons in the cat
The influence of chloral hydrate anesthesia on the spontaneous activity and responsiveness of serotonergic neurons was examined by administering chloral hydrate (300 mg/kg, i.p.) to freely movingExpand
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Self-administration of nalbuphine, butorphanol and pentazocine by morphine post-addict rats
The purpose of the study was to define possible self-administration of nalbuphine, butorphanol and pentazocine by morphine post-addict rats. Rats were prepared with permanent EEG and EMG electrodesExpand
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Response of dopaminergic neurons in cat to auditory stimuli presented across the sleep-waking cycle
The response of dopaminergic neurons of the substantia nigra pars compacta to auditory clicks continuously presented across the sleep-wake cycle was studied in cats. The initial excitatory followedExpand
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Caudate unit activity in freely moving cats: effects of phasic auditory and visual stimuli
Quantitative analyses of the single unit responses to sensory stimuli were made in caudate nucleus neurons in the unanesthetized freely moving cat. Over half of the cells were responsive toExpand
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Selective sigma receptor agonist and antagonist affect dopamine neuronal activity.
Extracellular recording techniques were used to study the effects of the selective sigma receptor agonist (+)-[3H]3-(3-hydroxyphenyl)-N-(1-propyl)piperidine ((+)-3-PPP) and selective sigma receptorExpand
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DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'-oxoethyl)- piperidine HBr], a sigma and 5-hydroxytryptamine2 receptor antagonist: receptor-binding, electrophysiological and
It has been suggested that sigma receptor antagonists may be useful as antipsychotic drugs and that 5-hydroxytryptamine (5-HT2) receptor antagonists produce improvements of the negative symptoms ofExpand
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