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Erythropoietin: Powerful protection of ischemic and post-ischemic brain
Ischemic brain injury inflicted by stroke and cardiac arrest ranks among the leading causes of death and long-term disability in the United States. The brain consumes large amounts of metabolicExpand
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Featured Article: Pyruvate preserves antiglycation defenses in porcine brain after cardiac arrest
Cardiac arrest (CA) and cardiocerebral resuscitation (CCR)-induced ischemia–reperfusion imposes oxidative and carbonyl stress that injures the brain. The ischemic shift to anaerobic glycolysis,Expand
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Vasopressin instead of epinephrine enhances efficacy of CPR without causing tachycardia (1150.5)
Survival from cardiac arrest is highly dependent on the arterial pressure generated by cardiopulmonary resuscitation (CPR). To increase efficacy of precordial compressions, the potent vasoconstrict...
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Novel Split Chest Tube Improves Post-Surgical Thoracic Drainage
Objective Conventional, separate mediastinal and pleural tubes are often inefficient at draining thoracic effusions. Description We developed a Y-shaped chest tube with split ends that divide withinExpand
Abstract 508: Pyruvate Induction of Glyoxalase 1 in Porcine Brain Post-cardiac Arrest: Enhanced Methylglyoxal and Glutamate Detoxification
Background: After cardiac arrest (CA) and cardio-cerebral resuscitation (CCR), enhanced glycolysis elevates toxic methylglyoxal (MG) that contributes to carbonyl-exacerbated oxidative stress, enzymeExpand