CYTOTOXIC AGENTS FROM NIGERIAN PLANTS : A CASE STUDY OF Spondias mombin LINN ( ANACARDIACEAE ) LEAVES
In this work, six Nigerian plants traditionally used to manage inflammation and cancer have been screened for cytotoxicity against brine shrimps with the aim of assessing their potential as…
In Vivo Antiplasmodial and Analgesic Effect of Crude Ethanol Extract of Piper guineense Leaf Extract in Albino Mice
- A. Kabiru, G. F. Ibikunle, D. Innalegwu, B. Bola, F. Madaki
- Biology, MedicineScientifica
- 30 June 2016
Results obtained in this study demonstrated the efficacy of ethanol extract of Piper guineense as an antiplasmodial and analgesic agent and the extract was safe at 2000 mg/kg body weight.
Effect of partially purified sub-fractions of Pterocarpus mildbraedii extract on carbon tetrachloride intoxicated rats
- R. Hamzah, A. A. Jigam, S. Abubakar-Akanbi
- Biology, MedicineIntegrative Medicine Research
- 2 February 2018
In-vitro evaluation of anti-trichomonal activities of Eugenia uniflora leaf.
- G. F. Ibikunle, A. C. Adebajo, F. Famuyiwa, A. J. Aladesanmi, C. Adewunmi
- BiologyAfrican Journal of Traditional Complementary and…
- 2011
The established safety of the leaf indicated that its anti-trichomonal activity was not due to non-specific cytotoxicity, hence could be used in ethnomedicine as an anti- Trichomonas gallinae agent.
Anti-plasmodial, Anti-inflammatory, anti-nociceptive and safety profile of Maytenus senegalensis root bark extract on hepato-renal integrity in experimental animals
- S. Umar, Muhammad Ndako, A. Jigam, S. F. Adefolalu, G. F. Ibikunle, B. Lawal
- BiologyComparative Clinical Pathology
- 2 May 2019
The extract alters some functional integrity of kidney, and thus caution should be exercised when using the extract for the above pharmacological activities or other oral remedy.
The identification of putative antitrypanosomal compounds in Tridax procumbens extracts
- A. Abubakar, E. Ogbadoyi, J. Okogun, T. I. Gbodi, G. F. Ibikunle
- Chemistry
- 2012
The therapeutic potential of Tridax procumbens extracts were screened for antitrypanosomal properties in mice. Whole T. procumbens was sequentially extracted with hexane, ethyl acetate, methanol and…
In Vitro Evaluation of Extracts of Solanum torvum (Solanaceae) Fruits for Anti-Trichomonal Activity
- G. F. Ibikunle, E. Ogbadoyi
- Chemistry
- 25 May 2016
It is concluded that methanol extracts of the fruits of Solanum torvum are a potential source of drug (s) for the treatment of trichomoniasis.