• Publications
  • Influence
Tissue sulfhydryl groups.
  • G. Ellman
  • Chemistry, Medicine
  • Archives of biochemistry and biophysics
  • 1 May 1959
Abstract A water-soluble (at pH 8) aromatic disulfide [5,5′-dithiobis(2-nitrobenzoic acid)] has been synthesized and shown to be useful for determination of sulfhydryl groups. Several applicationsExpand
A new and rapid colorimetric determination of acetylcholinesterase activity.
TLDR
A photometric method for determining acetylcholinesterase activity of tissue extracts, homogenates, cell suspensions, etc., has been described and Kinetic constants determined by this system for erythrocyte eholinesterases are presented. Expand
A colorimetric method for determining low concentrations of mercaptans.
  • G. Ellman
  • Chemistry, Medicine
  • Archives of biochemistry and biophysics
  • 1 April 1958
TLDR
A study of the specificity of the reaction indicates that it occurs only with the S − group (actual or potential, as in thiourea), and heavy-metal ions interfere with the reaction by irreversibly bonding any S − ions. Expand
A methodology for analysis of tissue sulfhydryl components.
TLDR
A methodology is described for the analysis of tissue SH components of a single tissue sample in terms of soluble and insoluble, reactive and unreactive, SH, using the SH reagent DTNB. Expand
A precise method for the determination of whole blood and plasma sulfhydryl groups.
TLDR
Studies of the stability of stored blood samples indicate that whole blood, but not plasma, can be kept refrigerated for several days without significant loss of sulfhydryl reaction. Expand
Erythrocyte Cholinesterase-levels in Mental Patients
TLDR
This work was an attempt to repeat Rubin's findings in larger groups of patients and normals, and showed a bimodal distribution of this enzyme in schizophrenic patients. Expand
Disulfide and sulfhydryl compounds in TCA extracts of human blood and plasma.
  • G. Ellman, H. Lysko
  • Chemistry, Medicine
  • The Journal of laboratory and clinical medicine
  • 1 September 1967
TRITON SOLUBILIZED ACETYLCHOLINESTERASE OF BRAIN
  • I. Ho, G. Ellman
  • Chemistry, Medicine
  • Journal of neurochemistry
  • 1 November 1969
TLDR
The enzyme which was extracted by Triton X‐100 is probably the precursor of the more water‐soluble enzyme that can be prepared from brain tissue by treatment with venom or protease. Expand
MOTHER'S MILK AND CHLORPROMAZINE
TLDR
This study suggests that babies of mothers receiving large doses of chlorpromazine can be safely breast-fed. Expand
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