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Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline.
OBJECTIVE The aim was to formulate clinical practice guidelines for pheochromocytoma and paraganglioma (PPGL). PARTICIPANTS The Task Force included a chair selected by the Endocrine SocietyExpand
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Catecholamine Metabolism: A Contemporary View with Implications for Physiology and Medicine
This article provides an update about catecholamine metabolism, with emphasis on correcting common misconceptions relevant to catecholamine systems in health and disease. Importantly, most metabolismExpand
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Sources and Significance of Plasma Levels of Catechols and Their Metabolites in Humans
Human plasma contains several catechols, including the catecholamines norepinephrine, epinephrine, and dopamine, their precursor, l-3,4-dihydroxyphenylalanine (l-DOPA), and their deaminatedExpand
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Overflow of catecholamine neurotransmitters to the circulation: source, fate, and functions.
Article de synthese sur l'efflux des neurotransmetteurs catecholaminergiques chez les mammiferes. Origine des catecholamines: la noradrenaline, l'adrenaline et la dopamine dans le plasma et l'urine.Expand
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The role of neuronal and extraneuronal plasma membrane transporters in the inactivation of peripheral catecholamines.
  • G. Eisenhofer
  • Medicine, Biology
  • Pharmacology & therapeutics
  • 1 July 2001
Catecholamines are translocated across plasma membranes by transporters that belong to two large families with mainly neuronal or extraneuronal locations. In mammals, neuronal uptake ofExpand
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Malignant pheochromocytoma: current status and initiatives for future progress.
Pheochromocytomas are rare catecholamine-producing neuroendocrine tumors that are usually benign, but which may also present as or develop into a malignancy. Predicting such behavior is notoriouslyExpand
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Pheochromocytomas in von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2 display distinct biochemical and clinical phenotypes.
This study examined the mechanisms linking different biochemical and clinical phenotypes of pheochromocytoma in multiple endocrine neoplasia type 2 (MEN 2) and von Hippel-Lindau (VHL) syndrome toExpand
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Biochemical diagnosis of pheochromocytoma: how to distinguish true- from false-positive test results.
Measurements of plasma normetanephrine and metanephrine provide a highly sensitive test for diagnosis of pheochromocytoma, but false-positive results remain a problem. We therefore assessedExpand
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Substantial production of dopamine in the human gastrointestinal tract.
Considerable urinary excretion of dopamine metabolites indicates that large amounts of dopamine are produced in unknown locations of the body. This study assessed the contribution of mesentericExpand
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Cardiovascular manifestations of phaeochromocytoma
Clinical expression of phaeochromocytoma may involve numerous cardiovascular manifestations, but usually presents as sustained or paroxysmal hypertension associated with other signs and symptoms ofExpand
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